Rabbit CCL2 Polyclonal Antibody | anti-CCL2 antibody

CCL2 Antibody

Cat. Num. AAA10976

• Gene Names: CCL2; HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: CCL2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: CCL2, Antibody; CCL2 Antibody; CCL2 antibody: HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30; C-C motif chemokine 2; HC11; chemokine (C-C motif) ligand 2; anti-CCL2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: CCL2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid; CCL2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 99

• Applicable Applications for anti-CCL2 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry-paraffin (IHC-P), Immunofluorescence (IF)
• Application Notes: CCL2 antibody can be used for detection of CCL2 by Western blot at 1 - 2 ug/mL.; Optimal dilutions for each application to be determined by the researcher.; Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples; and Immunofluorescence in human samples. All other applications and species not yet tested.
• Conjugate: Unconjugated
• Immunogen: Rabbit polyclonal CCL2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human CCL2.; The immunogen is located within the last 50 amino acids of CCL2.
• Homology: Predicted species reactivity based on immunogen sequence: Pig: (81%), Horse: (81%), Bovine: (75%), Rabbit: (75%), Guinea pig: (90%)
• Preparation and Storage: CCL2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

IF (Immunofluorescence)

(Immunofluorescence of CCL2 in human spleen tissue with CCL2 antibody at 20 μg/ml.)

IHC (Immunohistochemistry)

(Immunohistochemistry of CCL2 in human spleen tissue with CCL2 antibody at 5 μg/ml.)

WB (Western Blot)

(Western blot analysis of CCL2 in K562 cell lysate with CCL2 antibody at 1 μg/mL.)

Related Product Information for anti-CCL2 antibody

CCL2 Antibody: CCL2, also known as monocyte chemotactic protein 1 (MCP1), belongs to the intercrine beta (chemokine CC) family. It is produced by a variety of cell types and is a potent chemoattractant for monocytes, memory T lymphocytes, and natural killer (NK) cells. It is upregulated during infection and inflammation. CCL2 is a potent basophil activator but does not affect eosinophils, whereas the related protein MCP2 stimulates both eosinophils and basophils. MCP3 has been shown to have the broadest range of influence. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis.

NCBI and Uniprot Product Information

• NCBI GI #: 4506841
• NCBI GeneID: 6347
• NCBI Accession #: NP_002973
• NCBI GenBank Nucleotide #: NM_002982.3
• UniProt Accession #: P13500; Q9UDF3; B2R4V3
• Molecular Weight: Predicted: 11kDa; Observed: 14kDa
• NCBI Official Full Name: C-C motif chemokine 2
• NCBI Official Synonym Full Names: chemokine (C-C motif) ligand 2
• NCBI Official Symbol: CCL2
• NCBI Official Synonym Symbols: HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30
• NCBI Protein Information: C-C motif chemokine 2; small-inducible cytokine A2; monocyte secretory protein JE; monocyte chemotactic protein 1; monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
• UniProt Protein Name: C-C motif chemokine 2
• UniProt Gene Name: CCL2
• UniProt Synonym Gene Names: MCP1; SCYA2; MCAF; MCP-1
• UniProt Entry Name: CCL2_HUMAN