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product-image-AAA301784_IF13.jpg IF (Immunofluorescence) (Immunofluorescence analysis of U20S cell using CCND2 antibody. Blue: DAPI for nuclear staining.)

Rabbit CCND2 Polyclonal Antibody | anti-CCND2 antibody

CCND2 antibody

Gene Names
CCND2; MPPH3; KIAK0002
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
CCND2, Antibody; CCND2 antibody; KIAK0002; anti-CCND2 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total CCND2 antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
289
Applicable Applications for anti-CCND2 antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant Protein of human CCND2.
Target Name
CCND2
Preparation and Storage
Store at -20 degree C

IF (Immunofluorescence)

(Immunofluorescence analysis of U20S cell using CCND2 antibody. Blue: DAPI for nuclear staining.)

product-image-AAA301784_IF13.jpg IF (Immunofluorescence) (Immunofluorescence analysis of U20S cell using CCND2 antibody. Blue: DAPI for nuclear staining.)

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using CCND2 antibody.)

product-image-AAA301784_WB15.jpg WB (Western Blot) (Western blot analysis of extracts of various cell lines, using CCND2 antibody.)
Related Product Information for anti-CCND2 antibody
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors.
Product Categories/Family for anti-CCND2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
894
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33kd
NCBI Official Full Name
G1/S-specific cyclin-D2
NCBI Official Synonym Full Names
cyclin D2
NCBI Official Symbol
CCND2
NCBI Official Synonym Symbols
MPPH3; KIAK0002
NCBI Protein Information
G1/S-specific cyclin-D2
UniProt Protein Name
G1/S-specific cyclin-D2
UniProt Gene Name
CCND2
UniProt Entry Name
CCND2_HUMAN

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Product Notes

The CCND2 ccnd2 (Catalog #AAA301784) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCND2 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CCND2 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the CCND2 ccnd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCND2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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