WB (Western Blot)
(Western blot analysis of CCND2 (arrow) using rabbit polyclonal CCND2 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CCND2 gene.)
Rabbit anti-Human CCND2 Polyclonal Antibody | anti-CCND2 antibody
CCND2 Antibody (N-term)
Gene Names
CCND2; MPPH3; KIAK0002
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CCND2, Antibody; CCND2 Antibody (N-term); G1/S-specific cyclin-D2; CCND2; anti-CCND2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CCND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCND2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
1-30
Sequence Length
209
Applicable Applications for anti-CCND2 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of CCND2 (arrow) using rabbit polyclonal CCND2 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CCND2 gene.)
WB (Western Blot)
(Western blot analysis of CCND2 (arrow) using rabbit polyclonal CCND2 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CCND2 gene.)
WB (Western Blot)
(CCND2 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CCND2 antibody detected the CCND2 protein (arrow).)
WB (Western Blot)
(CCND2 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the CCND2 antibody detected the CCND2 protein (arrow).)
Related Product Information for anti-CCND2 antibody
The protein encoded by this gene belongs to the highly
conserved cyclin family, whose members are characterized by a
dramatic periodicity in protein abundance through the cell cycle.
Cyclins function as regulators of CDK kinases. Different cyclins
exhibit distinct expression and degradation patterns which
contribute to the temporal coordination of each mitotic event. This
cyclin forms a complex with and functions as a regulatory subunit
of CDK4 or CDK6, whose activity is required for cell cycle G1/S
transition. This protein has been shown to interact with and be
involved in the phosphorylation of tumor suppressor protein Rb.
Knockout studies of the homologous gene in mouse suggest the
essential roles of this gene in ovarian granulosa and germ cell
proliferation. High level expression of this gene was observed in
ovarian and testicular tumors.
conserved cyclin family, whose members are characterized by a
dramatic periodicity in protein abundance through the cell cycle.
Cyclins function as regulators of CDK kinases. Different cyclins
exhibit distinct expression and degradation patterns which
contribute to the temporal coordination of each mitotic event. This
cyclin forms a complex with and functions as a regulatory subunit
of CDK4 or CDK6, whose activity is required for cell cycle G1/S
transition. This protein has been shown to interact with and be
involved in the phosphorylation of tumor suppressor protein Rb.
Knockout studies of the homologous gene in mouse suggest the
essential roles of this gene in ovarian granulosa and germ cell
proliferation. High level expression of this gene was observed in
ovarian and testicular tumors.
Product Categories/Family for anti-CCND2 antibody
References
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Park, T.J., et al. J. Hum. Genet. 55(7):416-420(2010)
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Kosmaczewska, A., et al. Oncol. Res. 18 (2-3), 127-131 (2009) :
Park, T.J., et al. J. Hum. Genet. 55(7):416-420(2010)
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
Kosmaczewska, A., et al. Oncol. Res. 18 (2-3), 127-131 (2009) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33067
NCBI Official Full Name
G1/S-specific cyclin-D2
NCBI Official Synonym Full Names
cyclin D2
NCBI Official Symbol
CCND2
NCBI Official Synonym Symbols
MPPH3; KIAK0002
NCBI Protein Information
G1/S-specific cyclin-D2
UniProt Protein Name
G1/S-specific cyclin-D2
UniProt Gene Name
CCND2
UniProt Entry Name
CCND2_HUMAN
Similar Products
Product Notes
The CCND2 ccnd2 (Catalog #AAA286587) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The CCND2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCND2 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CCND2 ccnd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCND2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.