WB (Western Blot)
(Western blot analysis of CCR3 in human spleen tissue lysates with CCR3 antibody at 1 (lane 1) and 2 ug/mL (lane 2), and 2 ug/mL in the presence of blocking peptide (lane 3).)
Rabbit CCR3 Polyclonal Antibody | anti-CCR3 antibody
CCR3 Antibody
Gene Names
CCR3; CKR3; CD193; CMKBR3; CC-CKR-3
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Immunoaffinity purified IgG
Synonyms
CCR3, Antibody; CCR3 Antibody; CC chemokine receptor 3, eosinophil eotaxin receptor; anti-CCR3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Immunoaffinity purified IgG
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Concentration
1mg/ml (varies by lot)
Sequence Length
355
Applicable Applications for anti-CCR3 antibody
WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 14 amino acid peptide from near the amino terminus of human CCR3.
Target Name
CCR3
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
WB (Western Blot)
(Western blot analysis of CCR3 in human spleen tissue lysates with CCR3 antibody at 1 (lane 1) and 2 ug/mL (lane 2), and 2 ug/mL in the presence of blocking peptide (lane 3).)
WB (Western Blot)
(Western blot analysis of CCR3 in human spleen tissue lysates with CCR3 antibody at 1 (lane 1) and 2 ug/mL (lane 2), and 2 ug/mL in the presence of blocking peptide (lane 3).)
Related Product Information for anti-CCR3 antibody
Human immunodeficiency virus (HIV) and related virus require coreceptors to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b, CCR8, GPR15, STRL33, and CX3CR1 in the chemokine receptor family were recently identified as HIV coreceptors. CCR5, CXCR4 and CCR3 are the principal receptors for HIV fusion and entry of target cells. CCR3 facilitates infection by a subset of virus. CCR3 and CCR5 promote efficient infection of microglia, the major target cells in the CNS. High levels of CCR3 and CXCR4 expression were found on the neurons from both the central and peripheral nervous systems. The CCR3 ligand, eotaxin, and an anti-CCR3 antibody inhibited HIV infection of microglia. These results indicate CCR3 plays an important role in HIV infection of CNS.
Product Categories/Family for anti-CCR3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,453 Da
NCBI Official Full Name
C-C chemokine receptor type 3 isoform 1
NCBI Official Synonym Full Names
chemokine (C-C motif) receptor 3
NCBI Official Symbol
CCR3
NCBI Official Synonym Symbols
CKR3; CD193; CMKBR3; CC-CKR-3
NCBI Protein Information
C-C chemokine receptor type 3
UniProt Protein Name
C-C chemokine receptor type 3
UniProt Gene Name
CCR3
UniProt Synonym Gene Names
CMKBR3; C-C CKR-3; CC-CKR-3; CCR-3; CCR3; CKR3
UniProt Entry Name
CCR3_HUMAN
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Product Notes
The CCR3 ccr3 (Catalog #AAA307477) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCR3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CCR3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the CCR3 ccr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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