WB (Western Blot)
(The cell lysate derived from Jurkat was immunobloted by the Rabbit anti CCR8 (AAA71298) @1:500. An immunoreactive band is observed at ~40 kDa.)
Rabbit CCR8 Polyclonal Antibody | anti-CCR8 antibody
Rabbit anti CCR8 Polyclonal Antibody
Gene Names
CCR8; CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8
Applications
Immunohistochemistry, Immunoprecipitation, ELISA, Western Blot
Purity
The rabbit polyclonal antibody is purified by Affinity Purification.
Synonyms
CCR8, Antibody; Rabbit anti CCR8 Polyclonal Antibody; C-C chemokine receptor type 8; CC-CKR-8; CCR-8; CDw198; CKRL1; anti-CCR8 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
This antibody reacts with human CCR8. The other species are not tested.
Purity/Purification
The rabbit polyclonal antibody is purified by Affinity Purification.
Form/Format
This affinity purified antibody is supplied in sterile Phosphate-buffered saline (pH7.2) containing antibody stabilizer
Applicable Applications for anti-CCR8 antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation), ELISA, WB (Western Blot)
Positive Control
Jurkat Cells, Thumus
Cellular Location
Cell Membrane
Preparation and Storage
The antibodies are stable for 24 months from date of receipt when stored at –20°C to –70°C. The antibodies can be stored at 2°C-8°C for three months without detectable loss of activity. Avoid repeated freezing-thawing cycles.
WB (Western Blot)
(The cell lysate derived from Jurkat was immunobloted by the Rabbit anti CCR8 (AAA71298) @1:500. An immunoreactive band is observed at ~40 kDa.)
WB (Western Blot)
(The cell lysate derived from Jurkat was immunobloted by the Rabbit anti CCR8 (AAA71298) @1:500. An immunoreactive band is observed at ~40 kDa.)
Related Product Information for anti-CCR8 antibody
CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural-killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes.
References
Mutalithas, K., Guillen, C., Raport, C., Kolbeck, R., Soler, D., Brightling, C.E., Pavord, I.D. and Wardlaw, A.J. Expression of CCR8 is increased in asthma. Clin. Exp. Allergy 40 (8), 1175-1185 (2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40 kDa
NCBI Official Full Name
C-C chemokine receptor type 8
NCBI Official Synonym Full Names
C-C motif chemokine receptor 8
NCBI Official Symbol
CCR8
NCBI Official Synonym Symbols
CY6; TER1; CCR-8; CKRL1; CDw198; CMKBR8; GPRCY6; CMKBRL2; CC-CKR-8
NCBI Protein Information
C-C chemokine receptor type 8
UniProt Protein Name
C-C chemokine receptor type 8
UniProt Gene Name
CCR8
UniProt Synonym Gene Names
CKRL1; CMKBR8; CMKBRL2; C-C CKR-8; CC-CKR-8; CCR-8; CKR-L1; GPRCY6
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Product Notes
The CCR8 ccr8 (Catalog #AAA71298) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CCR8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CCR8 ccr8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCR8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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