Application Data
(Immunocytochemical staining of HepG2 cells with Rabbit anti Human CD107b (AAA50059))
Rabbit anti-Mouse CD107b Polyclonal Antibody | anti-CD107b antibody
RABBIT ANTI HUMAN CD107b
Gene Names
LAMP2; LAMPB; CD107b; LAMP-2; LGP110
Reactivity
Mouse
Applications
Western Blot, Immunohistochemistry
Synonyms
CD107b, Antibody; RABBIT ANTI HUMAN CD107b; anti-CD107b antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
This item recognises CD107b, also known as LAMP-2, a single-pass type I membrane protein belonging to the LAMP family.
CD107b is a transmembrane glycoprotein that is associated with lysosomal membranes and is primarily expressed on mononuclear phagocytes. Expression of CD107b varies between cell populations and the molecular weight of CD107b can vary between 92-120kD. This item migrates at 115 kDa in SDS page.
Studies suggest that CD107b may be involved in a range of cellular processes including leukocyte adhesion, protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome along with inter- and intracellular signal transduction. CD107b has also been implicated in tumour metastasis.
CD107b is a transmembrane glycoprotein that is associated with lysosomal membranes and is primarily expressed on mononuclear phagocytes. Expression of CD107b varies between cell populations and the molecular weight of CD107b can vary between 92-120kD. This item migrates at 115 kDa in SDS page.
Studies suggest that CD107b may be involved in a range of cellular processes including leukocyte adhesion, protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome along with inter- and intracellular signal transduction. CD107b has also been implicated in tumour metastasis.
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (varies by lot)
Sequence Length
411
Applicable Applications for anti-CD107b antibody
WB (Western Blot), IHC (Immunohistochemistry)
Perservative Stabilisers
0.02% Sodium Azide (NaN3)
Immunogen
A peptide corresponding to an 17 amino acid sequence from near the carboxyl terminus of human CD107b.
Histology Positive Control Tissue
Histology Positive Control Tissue
Antiserum Preparation
Antiserum to human CD107b was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Immunocytochemical staining of HepG2 cells with Rabbit anti Human CD107b (AAA50059))
Application Data
(Immunocytochemical staining of HepG2 cells with Rabbit anti Human CD107b (AAA50059))
Application Data
(Western blot analysis of whole cell lysate from HepG2 human hepatocellular carcinoma cells probed with Rabbit anti Human CD107b, also known as LAMP-2 (AAA50059) at 1(A) and 2(B) ug/ml)
Application Data
(Western blot analysis of whole cell lysate from HepG2 human hepatocellular carcinoma cells probed with Rabbit anti Human CD107b, also known as LAMP-2 (AAA50059) at 1(A) and 2(B) ug/ml)
Related Product Information for anti-CD107b antibody
MBS223732 recognises CD107b, also known as LAMP-2, a single-pass type I membrane protein belonging to the LAMP family. CD107b is a transmembrane glycoprotein that is associated with lysosomal membranes and is primarily expressed on mononuclear phagocytes. Expression of CD107b varies between cell populations and the molecular weight of CD107b can vary between 92-120kD. MBS223732 migrates at 115 kDa in SDS page. Studies suggest that CD107b may be involved in a range of cellular processes including leukocyte adhesion, protection of the lysosomal membrane from autodigestion, maintenance of the acidic environment of the lysosome along with inter- and intracellular signal transduction. CD107b has also been implicated in tumour metastasis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,170 Da
NCBI Official Full Name
lysosome-associated membrane glycoprotein 2 isoform C
NCBI Official Synonym Full Names
lysosomal-associated membrane protein 2
NCBI Official Symbol
LAMP2
NCBI Official Synonym Symbols
LAMPB; CD107b; LAMP-2; LGP110
NCBI Protein Information
lysosome-associated membrane glycoprotein 2; CD107 antigen-like family member B
UniProt Protein Name
Lysosome-associated membrane glycoprotein 2
UniProt Gene Name
LAMP2
UniProt Synonym Gene Names
LAMP-2; Lysosome-associated membrane protein 2
UniProt Entry Name
LAMP2_HUMAN
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Product Notes
The CD107b lamp2 (Catalog #AAA50059) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI HUMAN CD107b reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD107b can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD107b lamp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD107b, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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