WB (Western Blot)
(Western Blot analysis of MCF7 cells using CD110 Polyclonal Antibody. Secondary antibody was diluted at 1:20000)
Rabbit CD110 Polyclonal Antibody | anti-CD110 antibody
CD110 Rabbit Polyclonal Antibody
Gene Names
MPL; MPLV; TPOR; C-MPL; CD110; THCYT2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CD110, Antibody; CD110 Rabbit Polyclonal Antibody; MPL; TPOR; Thrombopoietin receptor; TPO-R; Myeloproliferative leukemia protein; Proto-oncogene c-Mpl; CD110; BH6842; anti-CD110 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
CD110 Polyclonal Antibody detects endogenous levels of CD110 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CD110 antibody
ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Synthesized peptide derived from Thrombopoietin receptor at AA range: 321-370
Modification
Unmodified/Total
Preparation and Storage
Store at -20 degree C/1 year
WB (Western Blot)
(Western Blot analysis of MCF7 cells using CD110 Polyclonal Antibody. Secondary antibody was diluted at 1:20000)
WB (Western Blot)
(Western Blot analysis of MCF7 cells using CD110 Polyclonal Antibody. Secondary antibody was diluted at 1:20000)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100)
IHC (Immunohistochemistry)
(Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100)
Related Product Information for anti-CD110 antibody
In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the human homologue, named, c-mpl, was cloned. Sequence data revealed that c-mpl encoded a protein that was homologous with members of the hematopoietic receptor superfamily. Presence of anti-sense oligodeoxynucleotides of c-mpl inhibited megakaryocyte colony formation. The ligand for c-mpl, thrombopoietin, was cloned in 1994. Thrombopoietin was shown to be the major regulator of megakaryocytopoiesis and platelet formation. The protein encoded by the c-mpl gene, CD110, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. TPO-R deficient mice were severely thrombocytopenic, emphasizing the important
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
65,521 Da
NCBI Official Full Name
thrombopoietin receptor
NCBI Official Synonym Full Names
MPL proto-oncogene, thrombopoietin receptor
NCBI Official Symbol
MPL
NCBI Official Synonym Symbols
MPLV; TPOR; C-MPL; CD110; THCYT2
NCBI Protein Information
thrombopoietin receptor; TPO-R; proto-oncogene c-Mpl; myeloproliferative leukemia protein; myeloproliferative leukemia virus oncogene
UniProt Protein Name
Thrombopoietin receptor
UniProt Gene Name
MPL
UniProt Synonym Gene Names
TPOR; TPO-R
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Product Notes
The CD110 mpl (Catalog #AAA318798) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD110 Rabbit Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD110 can be used in a range of immunoassay formats including, but not limited to, ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CD110 mpl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD110, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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