Rabbit CD184 Polyclonal Antibody | anti-CD184 antibody

RABBIT ANTI HUMAN CD184 (N-TERMINAL)

Cat. Num. AAA49942

• Gene Names: CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; D2S201E
• Applications: Western Blot, Immunoprecipitation, Flow Cytometry, Functional Assay, Immunohistochemistry
• Synonyms: CD184, Antibody; RABBIT ANTI HUMAN CD184 (N-TERMINAL); anti-CD184 antibody

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This item recognises the human G-protein-coupled chemokine receptor CD184 (CXCR4), a 40kDa cell surface protein known to act as a co-factor in HIV infection of CD4+ T cells. Mutations in the CD184 gene are associated with WHIM syndrome, an inherited combined immunodeficiency disease, see Taniuchi, S. et al. for details.
• Form/Format: Purified; Purified IgG - liquid
• Concentration: IgG concentration 0.5 mg/ml (varies by lot)
• Sequence Length: 356

• Applicable Applications for anti-CD184 antibody: WB (Western Blot), IP (Immunoprecipitation), FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry)
• Perservative Stabilisers: 0.09% Sodium Azide (NaN3) ; Preparation
• Immunogen: Peptide sequence corresponding to amino acids 1-14 of human CD184.; Buffer Solution
• Antiserum Preparation: Antisera to human CD184 were raised by repeated immunisation of rabbits with highly purified antigen.
• Target Species: Human
• Preparation and Storage: Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.; Shelf Life: 18 months from date of despatch.

Application Data

(Immunocytochemical staining of HeLa cells with Rabbit anti Human CD184 (AAA49942))

Application Data

(Western Blot analysis of HeLa whole cell lysate probed with Rabbit anti Human CD184 (AAA49942))

Related Product Information for anti-CD184 antibody

Rabbit anti Human CD184 antibody recognizes the human G-protein-coupled chemokine receptor CD184, also known as CXCR4. CD184 is a 352 amino acid ~40kDa cell surface protein known to act as a co-factor in HIV infection of CD4+ T cells (Bleul et al.. Mutations in the CD184 gene are associated with WHIM syndrome, an inherited combined immunodeficiency disease (Taniuchi et al..).

NCBI and Uniprot Product Information

• NCBI GI #: 56790927
• NCBI GeneID: 7852
• NCBI Accession #: NP_001008540.1
• NCBI GenBank Nucleotide #: NM_001008540.1
• UniProt Accession #: P61073; O60835; P30991; P56438; Q53S69; Q9BXA0; Q9UKN2; B2R5N0
• Molecular Weight: 40,221 Da
• NCBI Official Full Name: C-X-C chemokine receptor type 4 isoform a
• NCBI Official Synonym Full Names: chemokine (C-X-C motif) receptor 4
• NCBI Official Symbol: CXCR4
• NCBI Official Synonym Symbols: FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; D2S201E
• NCBI Protein Information: C-X-C chemokine receptor type 4; CD184 antigen; LPS-associated protein 3; SDF-1 receptor; fusin; leukocyte-derived seven transmembrane domain receptor; lipopolysaccharide-associated protein 3; neuropeptide Y receptor Y3; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor
• UniProt Protein Name: C-X-C chemokine receptor type 4
• UniProt Gene Name: CXCR4
• UniProt Synonym Gene Names: CXC-R4; CXCR-4; LESTR; LAP-3; LPS-associated protein 3; SDF-1 receptor
• UniProt Entry Name: CXCR4_HUMAN