IHC (Immunohiostchemistry)
(CD19 Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human CD19 Polyclonal Antibody | anti-CD19 antibody
CD19 Rabbit anti-Human Polyclonal Antibody
Gene Names
CD19; B4; CVID3; MGC12802
Reactivity
Human
Applications
Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
CD19, Antibody; CD19 Rabbit anti-Human Polyclonal Antibody; PathPlus CD19 Antibody; CD19; B-lymphocyte antigen CD19; CD19 molecule; Differentiation antigen CD19; T-cell surface antigen Leu-12; B4; CD19 antigen; CVID3; anti-CD19 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.1% Sodium Azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CD19 antibody
IHC (Immunohistochemistry)
Target
Human CD19
Immunogen
LP-10691, synthetic peptide
Conjugation
Unconjugated
Preparation and Storage
Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CD19 Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(CD19 Antibody-Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CD19 Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CD19 Antibody-Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-CD19 antibody
CD19 antibody is an unconjugated rabbit polyclonal antibody to CD19 from human. Validated for IHC.
CD19 is a transmembrane protein found in B cells other than plasma and follicular dendritic cells. CD19 is a necessary adaptor protein in signal transduction pathways that regulate B-cell differentiation and development. Additionally, mutations in CD19 have been associated with a decrease in antibody production in immunodeficiency syndromes and have also been implicated in autoimmune diseases. CD19 is a common marker for B-cells-it demonstrates positive membranous staining in B-cells in the mantle zone, germinal centers of lymphoid tissues, and in occasional plasma cells. In cancers, it is positive in B-cell lymphomas, most B-cell leukemia and in hairy cell leukemia. It is negative in T-cell lymphomas.
CD19 is a transmembrane protein found in B cells other than plasma and follicular dendritic cells. CD19 is a necessary adaptor protein in signal transduction pathways that regulate B-cell differentiation and development. Additionally, mutations in CD19 have been associated with a decrease in antibody production in immunodeficiency syndromes and have also been implicated in autoimmune diseases. CD19 is a common marker for B-cells-it demonstrates positive membranous staining in B-cells in the mantle zone, germinal centers of lymphoid tissues, and in occasional plasma cells. In cancers, it is positive in B-cell lymphomas, most B-cell leukemia and in hairy cell leukemia. It is negative in T-cell lymphomas.
References
Adv Exp Med Biol. 2005;560:125-39, PMID: 15934172; The Journal of Experimental Medicine. 1989 Dec. 170 (6): 2159 -64, PMID: 2479707; The New England Journal of Medicine. 2006 May. 354 (18): 1901 -12. PMID: 16672701; Leukemia & Lymphoma. 1995 Aug. 18 (5 -6): 385 -97, PMID: 8528044.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
61,128 Da
NCBI Official Full Name
B-lymphocyte antigen CD19 isoform 2
NCBI Official Synonym Full Names
CD19 molecule
NCBI Official Symbol
CD19
NCBI Official Synonym Symbols
B4; CVID3; MGC12802
NCBI Protein Information
B-lymphocyte antigen CD19; OTTHUMP00000122551; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4
UniProt Protein Name
B-lymphocyte antigen CD19
UniProt Gene Name
CD19
UniProt Entry Name
CD19_HUMAN
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Product Notes
The CD19 cd19 (Catalog #AAA162952) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD19 Rabbit anti-Human Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD19 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD19 cd19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD19, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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