Application Data
(Paraffin embedded human spleen stained with Goat anti mouse CD197 (AAA50065))
Goat anti-Human CD197 Polyclonal Antibody | anti-CD197 antibody
GOAT ANTI MOUSE CD197
Gene Names
CCR7; BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Functional Assay, Flow Cytometry, Functional Assay, ELISA
Synonyms
CD197, Antibody; GOAT ANTI MOUSE CD197; anti-CD197 antibody
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (varies by lot)
Sequence Length
378
Applicable Applications for anti-CD197 antibody
WB (Western Blot), IHC (Immunohistochemistry), FA (Functional Assay), FCM/FACS (Flow Cytometry), ELISA
Perservative Stabilisers
0.1% Sodium Azide
0.1% Bovine Serum Albumin.
0.1% Bovine Serum Albumin.
Histology Positive Control Tissue
Spleen.
Buffer Solution
Buffer Solution
Antiserum Preparation
Antiserum to mouse CD197 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Target Species
Mouse
Preparation and Storage
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Paraffin embedded human spleen stained with Goat anti mouse CD197 (AAA50065))
Application Data
(Paraffin embedded human spleen stained with Goat anti mouse CD197 (AAA50065))
Application Data
(Paraffin embedded mouse spleen stained with Goat anti mouse CD197 (AAA50065))
Application Data
(Paraffin embedded mouse spleen stained with Goat anti mouse CD197 (AAA50065))
Related Product Information for anti-CD197 antibody
Goat anti Mouse CD197 antibody recognizes mouse C-C chemokine receptor type 7, also known as CD197, CCR7, Epstein-Barr virus-induced G-protein coupled receptor 1 or MIP-3 beta receptor. CD197 is a 378 amino acid ~43 kDa multi pass type III transmembrane glycoprotein and member of the G-protein coupled receptor 1 family (UniProt: P74447). CD197 is expressed by various lymphoid tissues, activated B and T cells, naive T cells, NK cells and dendritic cells (DCs), which acts a high-affinity receptor for the chemokines MIP-3beta (CCL19) and CCL21. Ligand binding of CD197 plays a vital role in the homing of naive T cells and antigen-loaded DCs into secondary organs. Expression of CD197 is strongly up-regulated in B cells infected with Epstein-Barr virus (EBV) and T cells infected with herpesvirus 6 or 7. Goat anti Mouse CD197 antibody can be used in research studies to distinguish between central memory and effector memory T cells and is reported as suitable for use in immunocytochemistry.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,874 Da
NCBI Official Full Name
C-C chemokine receptor type 7
NCBI Official Synonym Full Names
chemokine (C-C motif) receptor 7
NCBI Official Symbol
CCR7
NCBI Official Synonym Symbols
BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7
NCBI Protein Information
C-C chemokine receptor type 7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; EBV-induced G protein-coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; MIP-3 beta receptor; lymphocyte-specific G protein-coupled peptide receptor
UniProt Protein Name
C-C chemokine receptor type 7
UniProt Gene Name
CCR7
UniProt Synonym Gene Names
CMKBR7; EBI1; EVI1; C-C CKR-7; CC-CKR-7; CCR-7; EBI1; EBV-induced G-protein coupled receptor 1
UniProt Entry Name
CCR7_HUMAN
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Product Notes
The CD197 ccr7 (Catalog #AAA50065) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The GOAT ANTI MOUSE CD197 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD197 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), FA (Functional Assay), FCM/FACS (Flow Cytometry), ELISA. Researchers should empirically determine the suitability of the CD197 ccr7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD197, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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