IHC (Immunohiostchemistry)
(CD1A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD1A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human CD1A Polyclonal Antibody | anti-CD1A antibody
CD1A Antibody (Center)
Gene Names
CD1A; R4; T6; CD1; FCB6; HTA1
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CD1A, Antibody; CD1A Antibody (Center); T-cell surface glycoprotein CD1a; T-cell surface antigen T6/Leu-6; hTa1 thymocyte antigen; CD1a; CD1A; anti-CD1A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CD1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human CD1A.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
75-104
Sequence Length
327
Applicable Applications for anti-CD1A antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CD1A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD1A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(CD1A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD1A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(CD1A Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the CD1A antibody detected the CD1A protein (arrow).)
WB (Western Blot)
(CD1A Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the CD1A antibody detected the CD1A protein (arrow).)
Related Product Information for anti-CD1A antibody
This gene encodes a member of the CD1 family of
transmembrane glycoproteins, which are structurally related to the
major histocompatibility complex (MHC) proteins and form
heterodimers with beta-2-microglobulin. The CD1 proteins mediate
the presentation of primarily lipid and glycolipid antigens of self
or microbial origin to T cells. The human genome contains five CD1
family genes organized in a cluster on chromosome 1. The CD1 family
members are thought to differ in their cellular localization and
specificity for particular lipid ligands. The protein encoded by
this gene localizes to the plasma membrane and to recycling
vesicles of the early endocytic system. Alternatively spliced
transcript variants have been observed, but their biological
validity has not been determined.
transmembrane glycoproteins, which are structurally related to the
major histocompatibility complex (MHC) proteins and form
heterodimers with beta-2-microglobulin. The CD1 proteins mediate
the presentation of primarily lipid and glycolipid antigens of self
or microbial origin to T cells. The human genome contains five CD1
family genes organized in a cluster on chromosome 1. The CD1 family
members are thought to differ in their cellular localization and
specificity for particular lipid ligands. The protein encoded by
this gene localizes to the plasma membrane and to recycling
vesicles of the early endocytic system. Alternatively spliced
transcript variants have been observed, but their biological
validity has not been determined.
Product Categories/Family for anti-CD1A antibody
References
Zeissig, S., et al. J. Clin. Invest. 120(8):2889-2899(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Valencia, J., et al. J. Leukoc. Biol. 87(3):405-414(2010)
Cernadas, M., et al. J. Immunol. 184(3):1235-1241(2010)
Young, D.C., et al. J. Biol. Chem. 284(37):25087-25096(2009)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Valencia, J., et al. J. Leukoc. Biol. 87(3):405-414(2010)
Cernadas, M., et al. J. Immunol. 184(3):1235-1241(2010)
Young, D.C., et al. J. Biol. Chem. 284(37):25087-25096(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37077
NCBI Official Full Name
T-cell surface glycoprotein CD1a
NCBI Official Synonym Full Names
CD1a molecule
NCBI Official Symbol
CD1A
NCBI Official Synonym Symbols
R4; T6; CD1; FCB6; HTA1
NCBI Protein Information
T-cell surface glycoprotein CD1a
UniProt Protein Name
T-cell surface glycoprotein CD1a
UniProt Gene Name
CD1A
UniProt Synonym Gene Names
hTa1 thymocyte antigen
UniProt Entry Name
CD1A_HUMAN
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Product Notes
The CD1A cd1a (Catalog #AAA285123) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 75-104. The CD1A Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD1A can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CD1A cd1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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