Rabbit anti-Human CD1C Polyclonal Antibody | anti-CD1C antibody

CD1C Antibody (C-term)

Cat. Num. AAA289045

• Gene Names: CD1C; R7; CD1; CD1A; BDCA1
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: CD1C, Antibody; CD1C Antibody (C-term); T-cell surface glycoprotein CD1c; CD1c; CD1C; anti-CD1C antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This CD1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the C-terminal region of human CD1C.
• Purity/Purification: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Vial Concentration: 0.27 (varies by lot)
• Sequence Positions: 226-253
• Sequence Length: 333

• Applicable Applications for anti-CD1C antibody: ELISA, WB (Western Blot)
• Antigen Type: Synthetic Peptide
• Antigen Source: HUMAN
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

WB (Western Blot)

(Western blot analysis of CD1C (arrow) using rabbit polyclonal CD1C Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CD1C gene.)

WB (Western Blot)

(CD1C Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD1C antibody detected the CD1C protein (arrow).)

Related Product Information for anti-CD1C antibody

This gene encodes a member of the CD1 family of
transmembrane glycoproteins, which are structurally related to the
major histocompatibility complex (MHC) proteins and form
heterodimers with beta-2-microglobulin. The CD1 proteins mediate
the presentation of primarily lipid and glycolipid antigens of self
or microbial origin to T cells. The human genome contains five CD1
family genes organized in a cluster on chromosome 1. The CD1 family
members are thought to differ in their cellular localization and
specificity for particular lipid ligands. The protein encoded by
this gene is broadly distributed throughout the endocytic system
via a tyrosine-based motif in the cytoplasmic tail. Alternatively
spliced transcript variants of this gene have been observed, but
their full-length nature is not known.

Product Categories/Family for anti-CD1C antibody

Immunology

References

Van Brussel, I., et al. J. Immunol. Methods 362 (1-2), 168-175 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Garzon, D., et al. Mol. Immunol. 47 (2-3), 253-260 (2009) :
Van Rhijn, I., et al. J. Exp. Med. 206(6):1409-1422(2009)
Kaser, A., et al. Eur. J. Immunol. 38(8):2351-2359(2008)

NCBI and Uniprot Product Information

• NCBI GI #: 110618227
• NCBI GeneID: 911
• NCBI Accession #: NP_001756.2
• NCBI GenBank Nucleotide #: NM_001765.2
• UniProt Accession #: P29017; Q5TDJ7; Q6IAS4; Q9UMM0; Q9UN96
• Molecular Weight: 37654
• NCBI Official Full Name: T-cell surface glycoprotein CD1c
• NCBI Official Synonym Full Names: CD1c molecule
• NCBI Official Symbol: CD1C
• NCBI Official Synonym Symbols: R7; CD1; CD1A; BDCA1
• NCBI Protein Information: T-cell surface glycoprotein CD1c
• UniProt Protein Name: T-cell surface glycoprotein CD1c
• UniProt Gene Name: CD1C
• UniProt Entry Name: CD1C_HUMAN