Application Data
(Immunocytochemical staining of Jurkat cells with Rabbit anti Human CD261 (AAA49940))
Rabbit CD261 Polyclonal Antibody | anti-CD261 antibody
RABBIT ANTI HUMAN CD261 (C-TERMINAL)
Gene Names
TNFRSF10A; DR4; APO2; CD261; TRAILR1; TRAILR-1
Applications
Western Blot, Immunohistochemistry
Synonyms
CD261, Antibody; RABBIT ANTI HUMAN CD261 (C-TERMINAL); anti-CD261 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
This item recognises the 57kD apoptosis related protein designated DR-4 (death receptor 4), also known as CD261.DR4 is a cell surface protein with a death domain that has functional similarities to TNFR1 and CD95. The ligand for DR-4 is TRAIL, and thus DR-4 has also been called TRAIL-RI. DR4 is expressed in most human tissues. In contrast to CD95, TNFR1 and DR3 it does not use FADD to transmit death signals.
Form/Format
Purified
Purified IgG - liquid
Purified IgG - liquid
Concentration
IgG concentration 0.5 mg/ml (varies by lot)
Sequence Length
468
Applicable Applications for anti-CD261 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Perservative Stabilisers
0.02% Sodium Azide
Immunogen
Peptide from C-terminus of human CD261 (DR4)
Buffer Solution
Buffer Solution
Antiserum Preparation
Antisera to CD261 (DR4) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Shelf Life: 18 months from date of despatch.
Application Data
(Immunocytochemical staining of Jurkat cells with Rabbit anti Human CD261 (AAA49940))
Application Data
(Immunocytochemical staining of Jurkat cells with Rabbit anti Human CD261 (AAA49940))
Application Data
(Western blot analysis of HeLa whole cell lysate probed with Rabbit anti Human CD261 (AAA49940))
Application Data
(Western blot analysis of HeLa whole cell lysate probed with Rabbit anti Human CD261 (AAA49940))
Related Product Information for anti-CD261 antibody
MBS221578 recognises the 57kD apoptosis related protein designated DR-4 (death receptor 4), also known as CD261. DR4 is a cell surface protein with a death domain that has functional similarities to TNFR1 and CD95. The ligand for DR-4 is TRAIL, and thus DR-4 has also been called TRAIL-RI. DR4 is expressed in most human tissues. In contrast to CD95, TNFR1 and DR3 it does not use FADD to transmit death signals.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,089 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 10A
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 10a
NCBI Official Symbol
TNFRSF10A
NCBI Official Synonym Symbols
DR4; APO2; CD261; TRAILR1; TRAILR-1
NCBI Protein Information
tumor necrosis factor receptor superfamily member 10A; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; cytotoxic TRAIL receptor; death receptor 4; tumor necrosis factor receptor superfamily member 10a variant 2
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 10A
UniProt Gene Name
TNFRSF10A
UniProt Synonym Gene Names
APO2; DR4; TRAILR1; TRAIL receptor 1; TRAIL-R1
UniProt Entry Name
TR10A_HUMAN
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Product Notes
The CD261 tnfrsf10a (Catalog #AAA49940) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CD261 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD261 tnfrsf10a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD261, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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