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product-image-AAA49915_AD13.gif Application Data (Immunocytochemical staining of EL4 mouse lymphoblast cells with Rabbit anti Human CD283 (AAA49915))

Rabbit anti-Mouse CD283 Polyclonal Antibody | anti-CD283 antibody

RABBIT ANTI HUMAN CD283

Gene Names
TLR3; CD283; IIAE2
Reactivity
Mouse
Applications
Western Blot, Immunohistochemistry
Synonyms
CD283, Antibody; RABBIT ANTI HUMAN CD283; anti-CD283 antibody
Ordering
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Form/Format
Purified
Purified IgG - liquid
Concentration
IgG concentration 1.0mg/ml (varies by lot)
Sequence Length
627
Applicable Applications for anti-CD283 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Perservative Stabilisers
0.02% Sodium Azide (NaN3)
Immunogen
Synthetic peptide corresponding to a 15 amino acid sequence located near human CD283 carboxy-terminus.
Buffer Solution
Antiserum Preparation
Antisera to human CD283 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by ion exchange chromatography.
Target Species
Human
Preparation and Storage
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.

Application Data

(Immunocytochemical staining of EL4 mouse lymphoblast cells with Rabbit anti Human CD283 (AAA49915))

product-image-AAA49915_AD13.gif Application Data (Immunocytochemical staining of EL4 mouse lymphoblast cells with Rabbit anti Human CD283 (AAA49915))

Application Data

(Western blot analysis of whole cell lysate from Daudi human Burkitt's lymphoma derived cells probed with Rabbit anti Human CD283 (AAA49915) at 1(A) and 2(B) ug/ml)

product-image-AAA49915_AD15.gif Application Data (Western blot analysis of whole cell lysate from Daudi human Burkitt's lymphoma derived cells probed with Rabbit anti Human CD283 (AAA49915) at 1(A) and 2(B) ug/ml)
Related Product Information for anti-CD283 antibody
Rabbit anti Human CD283 antibody recognizes human CD283, otherwise known as toll receptor 3, a 103.8kDa member of the evolutionarily conserved toll-like receptor family (TLRs), expressed at high levels in the placenta and pancreas and also expressed by dendritic cells. TLRs play an important role in the recognition of invading microbial pathogens during innate immunity, acting through adaptor molecules such as MyD88 and TRAF6. CD283 acts via a cytokine signaling pathway to induce the activation of NF-kappaB and type I interferons, and has been shown to recognize double-stranded viral RNA, including that of the Influenza A and West Nile virus. Rabbit anti Human CD283 antibody has been shown as suitable for use in IHC on EL4 cytospins at 1ug/ml.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
72,937 Da
NCBI Official Full Name
toll-like receptor 3
NCBI Official Synonym Full Names
toll-like receptor 3
NCBI Official Symbol
TLR3
NCBI Official Synonym Symbols
CD283; IIAE2
NCBI Protein Information
toll-like receptor 3
UniProt Protein Name
Toll-like receptor 3
UniProt Gene Name
TLR3
UniProt Entry Name
TLR3_HUMAN

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Product Notes

The CD283 tlr3 (Catalog #AAA49915) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABBIT ANTI HUMAN CD283 reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD283 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CD283 tlr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD283, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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