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IHC (Immunohistchemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
Rabbit anti-Human CD314 Polyclonal Antibody | anti-CD314 antibody
CD314 Polyclonal Antibody
Reactivity
Human
Applications
Immunohistochemistry
Synonyms
CD314; Polyclonal Antibody; CD314 Polyclonal Antibody; NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1)(NK cell receptor D)(NKG2-D-activating NK receptor)(CD antigen CD314); anti-CD314 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Applicable Applications for anti-CD314 antibody
Immunohistochemistry-Paraffin (IHC-P)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistchemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistchemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry-Paraffin)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
Related Product Information for anti-CD314 antibody
Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8 (+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, RAET1L/ULBP6, ulBP1, ulBP2, ulBP3 (ULBP2>ULBP1>ULBP3) andulBP4.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,274 Da
NCBI Official Full Name
NKG2-D type II integral membrane protein
NCBI Official Symbol
KLRC4-KLRK1
NCBI Protein Information
NKG2-D type II integral membrane protein; NK cell receptor D; NKG2-D-activating NK receptor; killer cell lectin-like receptor subfamily K member 1
UniProt Protein Name
NKG2-D type II integral membrane protein
UniProt Gene Name
KLRK1
UniProt Synonym Gene Names
D12S2489E; NKG2D
UniProt Entry Name
NKG2D_HUMAN
Similar Products
Product Notes
The CD314 klrk1 (Catalog #AAA29363) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD314 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD314 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). Researchers should empirically determine the suitability of the CD314 klrk1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD314, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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