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IHC (Immunohistochemistry)
(CD95/FAS Antibody-Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit CD95/FAS Polyclonal Antibody | anti-FAS antibody
CD95/FAS Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Gene Names
FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6
Reactivity
Mouse, Rat, Human
Applications
Western Blot, Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
CD95/FAS, Antibody; CD95/FAS Rabbit anti-Human Polyclonal (C-Terminus) Antibody; PathPlus CD95/FAS Antibody (C-Terminus); FAS; ALPS1A; APO-1; APT1; Apo-1 antigen; APO-1 cell surface antigen; Apo11 antigen; Apoptosis antigen 1; CD95 antigen; Delta Fas/APO-1/CD95; Fas AMA; FAS1; Fasl receptors; FASLG receptor; FASTM; FAS 827dupA; Fasl receptor; TNFRSF6; CD95; anti-FAS antibody
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of CD95 protein.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, pH7.3, 0.01% Sodium Azide, 30% Glycerol
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-FAS antibody
WB (Western Blot), IHC (Immunohistochemistry)
Target
Human CD95/FAS
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-Terminus of human CD95.
Conjugation
Unconjugated
Epitope
C-Terminus
Family
TNF Receptor
Preparation and Storage
Store at -20 degree C. Aliquot to avoid freeze/thaw cycles.
IHC (Immunohistochemistry)
(CD95/FAS Antibody-Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CD95/FAS Antibody-Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemisry)
(CD95/FAS Antibody-Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemisry)
(CD95/FAS Antibody-Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(CD95/FAS Antibody-Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(CD95/FAS Antibody-Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))
WB (Western Blot)
(CD95/FAS Antibody-Western blot analysis of CD95 expression in HeLa (A); A431 (B); K562 (C); HL60 (D); mouse brain (E); H9C2 (F) whole cell lysates.)
WB (Western Blot)
(CD95/FAS Antibody-Western blot analysis of CD95 expression in HeLa (A); A431 (B); K562 (C); HL60 (D); mouse brain (E); H9C2 (F) whole cell lysates.)
Related Product Information for anti-FAS antibody
FAS antibody is an unconjugated rabbit polyclonal antibody to FAS (CD95)(C-Terminus) from human. It is reactive with human, mouse and rat. Validated for IHC and WB.
FAS receptor (CD95, APO-1) is a transmembrane TNF death receptor that induces apoptosis via FAS ligand binding and is centrally involved in the regulation of programmed cell death. FAS receptor and its ligand FASLG are implicated in the pathogenesis of a number of cancers and immune diseases such as multiple sclerosis. FAS also plays a role in apoptotic cell loss in neurodegenerative diseases. Furthermore, it is upregulated and participates in phenylalanine-induced cell death in cortical neurons in patients with phenylalanine hydroxylase mutations, leading to childhood mental retardation. In immunohistochemistry, FAS has membranous and also secretory positivity at variable levels in most tissues throughout the body.
FAS receptor (CD95, APO-1) is a transmembrane TNF death receptor that induces apoptosis via FAS ligand binding and is centrally involved in the regulation of programmed cell death. FAS receptor and its ligand FASLG are implicated in the pathogenesis of a number of cancers and immune diseases such as multiple sclerosis. FAS also plays a role in apoptotic cell loss in neurodegenerative diseases. Furthermore, it is upregulated and participates in phenylalanine-induced cell death in cortical neurons in patients with phenylalanine hydroxylase mutations, leading to childhood mental retardation. In immunohistochemistry, FAS has membranous and also secretory positivity at variable levels in most tissues throughout the body.
References
Cell Death and Differentiation. 11 Suppl 1 (Suppl 1): S23 -7, PMID: 15143352; Nature. 465 (7297): 492 -6, PMID: 20505730; PLoS One. 2013 Aug 7;8(8):e71553, PMID: 23940767; Lab Invest. 1998 Apr;78(4):401-11, PMID: 9564885;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,732 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 6 isoform 1
NCBI Official Synonym Full Names
Fas cell surface death receptor
NCBI Official Symbol
FAS
NCBI Official Synonym Symbols
APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6
NCBI Protein Information
tumor necrosis factor receptor superfamily member 6; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; APO-1 cell surface antigen; TNF receptor superfamily member 6; apoptosis-mediating surface antigen FAS; Fas
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 6
UniProt Gene Name
FAS
UniProt Synonym Gene Names
APT1; FAS1; TNFRSF6
UniProt Entry Name
TNR6_HUMAN
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Product Notes
The FAS fas (Catalog #AAA163118) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD95/FAS Rabbit anti-Human Polyclonal (C-Terminus) Antibody reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's CD95/FAS can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the FAS fas for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD95/FAS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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