WB (Western Blot)
(CDC42EP2 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the CDC42EP2 antibody detected the CDC42EP2 protein (arrow).)
Rabbit anti-Human, mouse CDC42EP2 Polyclonal Antibody | anti-CDC42EP2 antibody
CDC42EP2 Antibody (C-term)
Gene Names
CDC42EP2; CEP2; BORG1
Reactivity
Human, mouse
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CDC42EP2, Antibody; CDC42EP2 Antibody (C-term); Cdc42 effector protein 2; Binder of Rho GTPases 1; CDC42EP2; BORG1; CEP2; anti-CDC42EP2 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CDC42EP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from the C-terminal region of human CDC42EP2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.3 (varies by lot)
Sequence Positions
133-160
Sequence Length
210
Applicable Applications for anti-CDC42EP2 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(CDC42EP2 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the CDC42EP2 antibody detected the CDC42EP2 protein (arrow).)
WB (Western Blot)
(CDC42EP2 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the CDC42EP2 antibody detected the CDC42EP2 protein (arrow).)
WB (Western Blot)
(CDC42EP2 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CDC42EP2 antibody detected the CDC42EP2 protein (arrow).)
WB (Western Blot)
(CDC42EP2 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CDC42EP2 antibody detected the CDC42EP2 protein (arrow).)
Related Product Information for anti-CDC42EP2 antibody
CDC42, a small Rho GTPase, regulates the formation of
F-actin-containing structures through its interaction with the
downstream effector proteins. The protein encoded by this gene is a
member of the Borg family of CDC42 effector proteins. Borg family
proteins contain a CRIB (Cdc42/Rac interactive-binding) domain.
They bind to, and negatively regulate the function of, CDC42.
Coexpression of this protein with dominant negative mutant CDC42
protein in fibroblast was found to induce pseudopodia formation,
which suggested a role of this protein in actin filament assembly
and cell shape control.
F-actin-containing structures through its interaction with the
downstream effector proteins. The protein encoded by this gene is a
member of the Borg family of CDC42 effector proteins. Borg family
proteins contain a CRIB (Cdc42/Rac interactive-binding) domain.
They bind to, and negatively regulate the function of, CDC42.
Coexpression of this protein with dominant negative mutant CDC42
protein in fibroblast was found to induce pseudopodia formation,
which suggested a role of this protein in actin filament assembly
and cell shape control.
Product Categories/Family for anti-CDC42EP2 antibody
References
Xue, Y., et al. Int. J. Cancer 118(12):2965-2972(2006)
Joberty, G., et al. Nat. Cell Biol. 3(10):861-866(2001)
Hirsch, D.S., et al. J. Biol. Chem. 276(2):875-883(2001)
Joberty, G., et al. Mol. Cell. Biol. 19(10):6585-6597(1999)
Burbelo, P.D., et al. Proc. Natl. Acad. Sci. U.S.A. 96(16):9083-9088(1999)
Joberty, G., et al. Nat. Cell Biol. 3(10):861-866(2001)
Hirsch, D.S., et al. J. Biol. Chem. 276(2):875-883(2001)
Joberty, G., et al. Mol. Cell. Biol. 19(10):6585-6597(1999)
Burbelo, P.D., et al. Proc. Natl. Acad. Sci. U.S.A. 96(16):9083-9088(1999)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22484
NCBI Official Full Name
cdc42 effector protein 2
NCBI Official Synonym Full Names
CDC42 effector protein (Rho GTPase binding) 2
NCBI Official Symbol
CDC42EP2
NCBI Official Synonym Symbols
CEP2; BORG1
NCBI Protein Information
cdc42 effector protein 2
UniProt Protein Name
Cdc42 effector protein 2
UniProt Gene Name
CDC42EP2
UniProt Synonym Gene Names
BORG1; CEP2
UniProt Entry Name
BORG1_HUMAN
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Product Notes
The CDC42EP2 cdc42ep2 (Catalog #AAA284365) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 133-160. The CDC42EP2 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CDC42EP2 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CDC42EP2 cdc42ep2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CDC42EP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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