Rabbit anti-Human CECR6 Polyclonal Antibody | anti-CECR6 antibody

CECR6 Antibody

Cat. Num. AAA310348

• Gene Names: TMEM121B; CECR6
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Antigen affinity purification
• Synonyms: CECR6, Antibody; CECR6 Antibody; anti-CECR6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: The antibody detects endogenous levels of total CECR6 protein.
• Purity/Purification: Antigen affinity purification
• Form/Format: In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
• Concentration: 0.8mg/ml (varies by lot)
• Sequence Length: 578

• Applicable Applications for anti-CECR6 antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen: Synthetic peptide corresponding to internal residues of human CECR6
• Immunogen Type: Peptide
• Preparation and Storage: Store at -20 degree C.

IHC (Immunohistochemisry)

(The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 46466(CECR6 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))

IHC (Immunohiostchemistry)

(The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 46466(CECR6 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200))

SDS-PAGE

(Gel: 8%SDS-PAGE lysate: 40 ¦Œg, Lane: Human heart tissue lysate, Primary antibody: 46466£¨CECR6 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)

Related Product Information for anti-CECR6 antibody

Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.

Product Categories/Family for anti-CECR6 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 13994236
• NCBI GeneID: 27439
• NCBI Accession #: NP_114096
• NCBI GenBank Nucleotide #: NM_031890.3
• UniProt Accession #: Q9BXQ6; A8MYY1
• Molecular Weight: 58 kDa
• NCBI Official Full Name: transmembrane protein 121B isoform a
• NCBI Official Synonym Full Names: transmembrane protein 121B
• NCBI Official Symbol: TMEM121B
• NCBI Official Synonym Symbols: CECR6
• NCBI Protein Information: transmembrane protein 121B; cat eye syndrome critical region protein 6
• UniProt Protein Name: Transmembrane protein 121B
• UniProt Gene Name: TMEM121B