IHC (Immunohiostchemistry)
(CELA3B Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CELA3B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human CELA3B Polyclonal Antibody | anti-CELA3B antibody
CELA3B Antibody (N-term)
Gene Names
CELA3B; E1; CBPP; EL-1; ELA3B
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CELA3B, Antibody; CELA3B Antibody (N-term); Chymotrypsin-like elastase family member 3B; Elastase IIIB; Elastase-3B; Protease E; CELA3B; ELA3B; anti-CELA3B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CELA3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human CELA3B.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
70-98
Sequence Length
270
Applicable Applications for anti-CELA3B antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CELA3B Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CELA3B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(CELA3B Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CELA3B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(CELA3B Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CELA3B antibody detected the CELA3B protein (arrow).)
WB (Western Blot)
(CELA3B Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CELA3B antibody detected the CELA3B protein (arrow).)
Related Product Information for anti-CELA3B antibody
Elastases form a subfamily of serine proteases that
hydrolyze many proteins in addition to elastin. Humans have six
elastase genes which encode the structurally similar proteins
elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase
3B has little elastolytic activity. Like most of the human
elastases, elastase 3B is secreted from the pancreas as a zymogen
and, like other serine proteases such as trypsin, chymotrypsin and
kallikrein, it has a digestive function in the intestine. Elastase
3B preferentially cleaves proteins after alanine residues. Elastase
3B may also function in the intestinal transport and metabolism of
cholesterol. Both elastase 3A and elastase 3B have been referred to
as protease E and as elastase 1, and excretion of this protein in
fecal material is frequently used as a measure of pancreatic
function in clinical assays.
hydrolyze many proteins in addition to elastin. Humans have six
elastase genes which encode the structurally similar proteins
elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase
3B has little elastolytic activity. Like most of the human
elastases, elastase 3B is secreted from the pancreas as a zymogen
and, like other serine proteases such as trypsin, chymotrypsin and
kallikrein, it has a digestive function in the intestine. Elastase
3B preferentially cleaves proteins after alanine residues. Elastase
3B may also function in the intestinal transport and metabolism of
cholesterol. Both elastase 3A and elastase 3B have been referred to
as protease E and as elastase 1, and excretion of this protein in
fecal material is frequently used as a measure of pancreatic
function in clinical assays.
Product Categories/Family for anti-CELA3B antibody
References
Gao, J., et al. Oncol. Rep. 23(6):1683-1692(2010)
Teichmann, J., et al. Eur. J. Med. Res. 13(12):563-567(2008)
Hahn, J.U., et al. Pancreas 36(3):274-278(2008)
Mann, S.T., et al. Eur. J. Med. Res. 13(2):68-72(2008)
Vesterhus, M., et al. Diabetes Care 31(2):306-310(2008)
Teichmann, J., et al. Eur. J. Med. Res. 13(12):563-567(2008)
Hahn, J.U., et al. Pancreas 36(3):274-278(2008)
Mann, S.T., et al. Eur. J. Med. Res. 13(2):68-72(2008)
Vesterhus, M., et al. Diabetes Care 31(2):306-310(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29263
NCBI Official Full Name
chymotrypsin-like elastase family member 3B preproprotein
NCBI Official Synonym Full Names
chymotrypsin-like elastase family, member 3B
NCBI Official Symbol
CELA3B
NCBI Official Synonym Symbols
E1; CBPP; EL-1; ELA3B
NCBI Protein Information
chymotrypsin-like elastase family member 3B
UniProt Protein Name
Chymotrypsin-like elastase family member 3B
UniProt Gene Name
CELA3B
UniProt Synonym Gene Names
ELA3B
UniProt Entry Name
CEL3B_HUMAN
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Product Notes
The CELA3B cela3b (Catalog #AAA284092) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 70-98. The CELA3B Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CELA3B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CELA3B cela3b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CELA3B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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