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ICC (Immunocytochemistry)
(ICC staining CELF2 in SHG-44 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
Rabbit CELF2 Polyclonal Antibody | anti-CELF2 antibody
CELF2 Antibody
Gene Names
CELF2; ETR3; ETR-3; NAPOR; CUGBP2; BRUNOL3
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Western Blot
Purity
Peptide affinity purified
Synonyms
CELF2, Antibody; CELF2 Antibody; Bruno-like protein 3 antibody; BRUNOL3 antibody; Cardiac elav type RNA binding protein antibody; CELF-2 antibody; celf2 antibody; CELF2_HUMAN antibody; CUG BP2 antibody; CUG triplet repeat RNA-binding protein 2 antibody; CUG-BP- and ETR-3-like factor 2 antibody; CUG-BP2 antibody; CUGBP Elav like family member 2 antibody; CUGBP Elav-like family member 2 antibody; CUGBP2 antibody; dJ323N1.1 antibody; elav type RNA binding protein antibody; ELAV-type RNA-binding protein 3 antibody; ETR 3 antibody; ETR-3 antibody; ETR3 antibody; HGNC:2550 antibody; hNAPOR antibody; NAPOR 2 antibody; NAPOR antibody; Neuroblastoma apoptosis-related RNA-binding protein antibody; Neuroplastoma apoptosis related RNA binding protein 3 antibody; RNA binding protein BRUNOL3 antibody; RNA-binding protein BRUNOL-3 antibody; anti-CELF2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Peptide affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-CELF2 antibody
ICC (Immunocytochemistry), WB (Western Blot)
Immunogen
Peptide
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
ICC (Immunocytochemistry)
(ICC staining CELF2 in SHG-44 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining CELF2 in SHG-44 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining CELF2 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining CELF2 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining CELF2 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
ICC (Immunocytochemistry)
(ICC staining CELF2 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.)
WB (Western Blot)
(Western blot analysis of CELF2 on Jurkat cell lysate using anti-CELF2 antibody at 1/2, 000 dilution.)
WB (Western Blot)
(Western blot analysis of CELF2 on Jurkat cell lysate using anti-CELF2 antibody at 1/2, 000 dilution.)
Related Product Information for anti-CELF2 antibody
Myotonic dystrophy (DM) is an autosomal dominant neuromuscular disease that is associated with a (CTG)n repeat expansion in the 3'-untranslated region of the myotonin protein kinase gene (DMPK). CUG-BP1 and CUG-BP2 are proteins that bind specifically to (CUG)8 oligonucleotides in vitro. While CUG-BP1 has the major binding activity in normal cells, nuclear CUG-BP2 binding activity increases in DM cells. Both CUG-BP1 and CUG-BP2 are isoforms of a novel heterogeneous nuclear ribonucleoprotein (hnRNP), hNab50. CUG-BP1, an RNA CUG triplet repeat binding protein, regulates splicing and translation of various RNAs. Expansion of RNA CUG repeats in the DMPK in DM is associated with alterations in binding activity of CUG-BP1 as well as alterations in the translation of the C/EBPb transcription factor. CUG-BP1 is an important regulator of initiation from different AUG codons of C/EBPb mRNA. In normal cells, CUG-BP1 up-regulates the p21 protein during differentiation by inducing the translation of p21 via binding to a GC-rich sequence located within the 5' region of p21 mRNA. In DM cells, failure to accumulate CUG-BP1 leads to a reduction of p21 and alterations in other proteins responsible for cell cycle withdrawl.
Product Categories/Family for anti-CELF2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,054 Da
NCBI Official Full Name
CUGBP Elav-like family member 2 isoform 2
NCBI Official Synonym Full Names
CUGBP, Elav-like family member 2
NCBI Official Symbol
CELF2
NCBI Official Synonym Symbols
ETR3; ETR-3; NAPOR; CUGBP2; BRUNOL3
NCBI Protein Information
CUGBP Elav-like family member 2; CELF-2; CUG-BP2; bruno-like protein 3; RNA-binding protein BRUNOL-3; CUG-BP- and ETR-3-like factor 2; ELAV-type RNA-binding protein 3; CUG triplet repeat RNA-binding protein 2; neuroblastoma apoptosis-related RNA-binding p
UniProt Protein Name
CUGBP Elav-like family member 2
UniProt Gene Name
CELF2
UniProt Synonym Gene Names
BRUNOL3; CUGBP2; ETR3; NAPOR; CELF-2; CUG-BP2; ETR-3; hNAPOR
UniProt Entry Name
CELF2_HUMAN
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Product Notes
The CELF2 celf2 (Catalog #AAA311947) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CELF2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CELF2 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CELF2 celf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CELF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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