Goat CFH / Complement Factor H Polyclonal Antibody | anti-CFH antibody

Goat Polyclonal to Human CFH / Complement Factor H

Cat. Num. AAA50891

• Gene Names: CFH; FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3
• Reactivity: Gibbon, Gorilla, Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: CFH / Complement Factor H, Antibody; Goat Polyclonal to Human CFH / Complement Factor H; Anti-CFH / Complement Factor H Antibody (Internal) IHC-plus; CFH; Adrenomedullin binding protein; AHUS1; AMBP1; ARMS1; ARMD4; Beta-1-H-globulin; Factor H; Factor H-like 1; HF; HF2; H factor 1; H factor 2 (complement); HUS; HF1; Beta-1H; CFHL3; Complement factor H; H factor 1 (complement); Human CFH; Complement Factor H; anti-CFH antibody

• Host: Goat
• Reactivity: Gibbon, Gorilla, Human
• Clonality: Polyclonal
• Specificity: Human CFH / Factor H. This antibody is expected to recognize isoform a (NP_000177.2) only.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 1231

• Applicable Applications for anti-CFH antibody: ELISA, WB (Western Blot), IHC (Immunohistochemistry)
• Target Species: Human
• Immunogen Description: Synthetic peptide C-HLVPDRKKDQYK from an internal region of human CFH / Factor H (NP_000177.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%).
• Immunogen Type: Synthetic peptide
• Immunogen: CFH / Complement Factor H antibody was raised against synthetic peptide C-HLVPDRKKDQYK from an internal region of human CFH / Factor H (NP_000177.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%).
• Antigen Modification: Internal
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

WB (Western Blot)

(Antibody staining (0.03 ug/ml) of human lung lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.)

IHC (Immunohistochemistry)

(Anti-Factor H antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Related Product Information for anti-CFH antibody

Factor H (CFH) is a protein with twenty short consensus repeat (SCR) domains. Factor H is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in Factor H have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

NCBI and Uniprot Product Information

• NCBI GI #: 62739186
• NCBI GeneID: 3075
• NCBI Accession #: NP_000177.2
• NCBI GenBank Nucleotide #: NM_000186.3
• UniProt Accession #: P08603; P78435; Q14570; Q2TAZ5; Q38G77; Q5TFM3; Q8N708; Q9NU86; A5PL14
• Molecular Weight: 51,034 Da
• NCBI Official Full Name: complement factor H isoform a
• NCBI Official Synonym Full Names: complement factor H
• NCBI Official Symbol: CFH
• NCBI Official Synonym Symbols: FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3
• NCBI Protein Information: complement factor H; beta-1H; factor H-like 1; beta-1-H-globulin; H factor 1 (complement); H factor 2 (complement); adrenomedullin binding protein; complement factor H, isoform b; age-related maculopathy susceptibility 1
• UniProt Protein Name: Complement factor H
• UniProt Gene Name: CFH
• UniProt Synonym Gene Names: HF; HF1; HF2
• UniProt Entry Name: CFAH_HUMAN