Rabbit anti-Human, Mouse CHD7 Polyclonal Antibody | anti-CHD7 antibody

CHD7 Antibody

Cat. Num. AAA39886

• Gene Names: CHD7; CRG; HH5; IS3; KAL5
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: CHD7 Antibody is affinity chromatography purified via peptide column.
• Synonyms: CHD7, Antibody; CHD7 Antibody; CHD7; CRG; HH5; IS3; KAL5; KIAA1416; Chromodomain-helicase-DNA-binding protein 7; ATP-dependent helicase CHD7; CHD-7; chromodomain helicase DNA binding protein 7; anti-CHD7 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Multiple isoforms of CHD7 are known to exist.
• Purity/Purification: CHD7 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 2997

• Applicable Applications for anti-CHD7 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: CHD7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CHD7.
• Buffer: CHD7 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: CHD7 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of CHD7 in mouse brain tissue with CHD7 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of CHD7 in mouse brain tissue with CHD7 antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of CHD7 in SK-N-SH cell lysate with CHD7 antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-CHD7 antibody

CHD7 Antibody: CHD proteins belong to a superfamily of proteins of ATP-dependent chromatin remodeling enzymes that have a unique combination of functional domains, including two N-terminal chromodomains, a SNF2-like ATPase/helicase domain and a DNA-binding domain. These proteins are thought to play a role in early embryonic development by affecting chromatin structure and gene expression. Mutations in one member of this family, CHD7, result in CHARGE syndrome. It colocalizes with embryonic stem (ES) cell master regulators OCT4/POU5F1, SOX2, and NANOG and is thought to modulate ES-specific gene transcription. Together with SOX2, CHD7 has been suggested to also regulate several human disease genes.

NCBI and Uniprot Product Information

• NCBI GI #: 54112403
• NCBI GeneID: 55636
• NCBI Accession #: NP_060250.2
• NCBI GenBank Nucleotide #: NM_017780.3
• UniProt Accession #: Q9P2D1; Q05DI5; Q2TAN4; Q66K35; Q7Z6C0; Q7Z7Q2; Q9NXA0; Q9NXA3; D0VBA5; E9PNZ2
• Molecular Weight: 101,085 Da
• NCBI Official Full Name: chromodomain-helicase-DNA-binding protein 7
• NCBI Official Synonym Full Names: chromodomain helicase DNA binding protein 7
• NCBI Official Symbol: CHD7
• NCBI Official Synonym Symbols: CRG; HH5; IS3; KAL5
• NCBI Protein Information: chromodomain-helicase-DNA-binding protein 7; CHARGE association; ATP-dependent helicase CHD7; chromodomain helicase DNA binding protein 7 isoform CRA_e
• UniProt Protein Name: Chromodomain-helicase-DNA-binding protein 7
• UniProt Gene Name: CHD7
• UniProt Synonym Gene Names: KIAA1416; CHD-7
• UniProt Entry Name: CHD7_HUMAN