IHC (Immunohiostchemistry)
(Immunohistochemistry of CIP75 in mouse kidney tissue with CIP75 antibody at 5 μg/mL.)
Rabbit CIP75 Polyclonal Antibody | anti-UBQLN4 antibody
CIP75 Antibody
Gene Names
UBQLN4; A1U; A1Up; UBIN; CIP75; C1orf6
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
CIP75 Antibody is affinity chromatography purified via peptide column.
Synonyms
CIP75, Antibody; CIP75 Antibody; CIP75; A1U; A1Up; UBIN; C1orf6; Ubiquilin-4; Ataxin-1 interacting ubiquitin-like protein; ubiquilin 4; anti-UBQLN4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
CIP75 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
601
Applicable Applications for anti-UBQLN4 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
CIP75 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CIP75.
Buffer
CIP75 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
CIP75 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of CIP75 in mouse kidney tissue with CIP75 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of CIP75 in mouse kidney tissue with CIP75 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of CIP75 in 3T3 cell lysate with CIP75 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of CIP75 in 3T3 cell lysate with CIP75 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-UBQLN4 antibody
CIP75 Antibody: The ubiquitin-proteosome pathway of protein degradation is one of the mechanisms that ensure the proper level of cellular proteins. The ubiquitin-like (UbL) and ubiquitin-associated (UBA) domain containing protein family is thought to be involved in proteosomal degradation. One such protein is CIP75, also known as ubiquilin-4, interacts with a number of proteins such as Ataxin-1 and Connexin-43, resulting in an increased rate of turnover of these proteins. Overexpression CIP75 led to a significant reduction of Connexin-43 half-life, with the opposite being observed in siRNA knockdown experiments. CIP75 contains an N-terminal UbL domain which is thought to interact with proteins of the 26S proteosome complex and a C-terminal UBA domain which appears to mediate its interaction with Connexin-75. At least three isoforms of CIP75 are known to exist.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
24,527 Da
NCBI Official Full Name
Ubiquilin-4
NCBI Official Synonym Full Names
ubiquilin 4
NCBI Official Symbol
UBQLN4
NCBI Official Synonym Symbols
A1U; A1Up; UBIN; CIP75; C1orf6
NCBI Protein Information
ubiquilin-4; connexin43-interacting protein of 75 kDa; ataxin-1 interacting ubiquitin-like protein; ataxin-1 ubiquitin-like interacting protein; ataxin-1 ubiquitin-like-interacting protein A1U
UniProt Protein Name
Ubiquilin-4
UniProt Gene Name
UBQLN4
UniProt Synonym Gene Names
C1orf6; CIP75; UBIN; A1Up; CIP75
UniProt Entry Name
UBQL4_HUMAN
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Product Notes
The UBQLN4 ubqln4 (Catalog #AAA40211) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CIP75 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CIP75 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the UBQLN4 ubqln4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CIP75, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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