WB (Western Blot)
(Western Blot of Lane 1: full-length CLAC-P (lysate), Lane 2: secreted form of CLAC-P (media), Lane 3: COLXIII (lysate), Lane 4 degrees COLXIII (media), Lane 5: COLXXIII (lysate), Lane 6: COLXXIII (media) showing specific immunolabeling of Collagen XXV alpha 1.)
Rabbit anti-Human, Mouse CLAC-P (NC3 region) Polyclonal Antibody | anti-COL25A1 antibody
Anti-CLAC-P (NC3 region) Antibody
Gene Names
COL25A1; AMY; CLAC; CLACP; CLAC-P
Reactivity
Human, Mouse
Applications
Western Blot
Synonyms
CLAC-P (NC3 region), Antibody; Anti-CLAC-P (NC3 region) Antibody; COL25A1; Collagen alpha-1 XXV chain; Alzheimer disease amyloid-associated protein; AMY; Collagen-like Alzheimer amyloid plaque component; CLAC-P (NC3 region); anti-COL25A1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Reacts with the NC3 region of human and mouse CLAC-P.
Form/Format
Liquid; Antigen Affinity Purified; PBS + 0.02% NaN3
Applicable Applications for anti-COL25A1 antibody
WB (Western Blot)
Immunogen Species
Human
Immunogen
Synthetic peptide corresponding to amino acids from the NC23 region of human CLAC-P
Country of Origin
United States
Preparation and Storage
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20 degree C or -80 degree C, while keeping a working aliquot stored at 4 degree C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
After date of receipt, stable for at least 1 year at -20 degree C.
After date of receipt, stable for at least 1 year at -20 degree C.
WB (Western Blot)
(Western Blot of Lane 1: full-length CLAC-P (lysate), Lane 2: secreted form of CLAC-P (media), Lane 3: COLXIII (lysate), Lane 4 degrees COLXIII (media), Lane 5: COLXXIII (lysate), Lane 6: COLXXIII (media) showing specific immunolabeling of Collagen XXV alpha 1.)
WB (Western Blot)
(Western Blot of Lane 1: full-length CLAC-P (lysate), Lane 2: secreted form of CLAC-P (media), Lane 3: COLXIII (lysate), Lane 4 degrees COLXIII (media), Lane 5: COLXXIII (lysate), Lane 6: COLXXIII (media) showing specific immunolabeling of Collagen XXV alpha 1.)
IHC (Immunohistochemistry)
(Immunohistochemistry of the neocortex of Alzheimer's diseased brain sections (floating, fixed with 10% formalin for 24 hrs) showing specific staining of Collagen XXV.)
IHC (Immunohistochemistry)
(Immunohistochemistry of the neocortex of Alzheimer's diseased brain sections (floating, fixed with 10% formalin for 24 hrs) showing specific staining of Collagen XXV.)
Related Product Information for anti-COL25A1 antibody
CLAC-P (NC3 region) rabbit polyclonal primary antibody from the lab is produced in-house. It detects human and mouse CLAC-P (NC3 region) and is antigen affinity purified. It is great for use in WB.
Antibodies against senile plaque (SP) amyloid obtained a clone 9D2, which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimer's disease (AD) brains. The 9D2 antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD
Antibodies against senile plaque (SP) amyloid obtained a clone 9D2, which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimer's disease (AD) brains. The 9D2 antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD
Product Categories/Family for anti-COL25A1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
64,771 Da
NCBI Official Full Name
collagen alpha-1(XXV) chain isoform 2
NCBI Official Synonym Full Names
collagen, type XXV, alpha 1
NCBI Official Symbol
COL25A1
NCBI Official Synonym Symbols
AMY; CLAC; CLACP; CLAC-P
NCBI Protein Information
collagen alpha-1(XXV) chain; collagen alpha-1(XXV) chain; alzheimer disease amyloid-associated protein; collagenous Alzheimer amyloid plaque component; collagen-like Alzheimer amyloid plaque component
UniProt Protein Name
Collagen alpha-1(XXV) chain
UniProt Gene Name
COL25A1
UniProt Synonym Gene Names
AMY; CLAC
UniProt Entry Name
COPA1_HUMAN
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Product Notes
The COL25A1 col25a1 (Catalog #AAA72769) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CLAC-P (NC3 region) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CLAC-P (NC3 region) can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the COL25A1 col25a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLAC-P (NC3 region), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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