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product-image-AAA39361_IF13.jpg IF (Immunofluorescence) (Immunofuorescence of CLIP170 in human brain tissue with CLIP170 antibody at 20 μg/mL.)

Rabbit CLIP170 Polyclonal Antibody | anti-CLIP1 antibody

CLIP170 Antibody

Gene Names
CLIP1; RSN; CLIP; CYLN1; CLIP170; CLIP-170
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, ELISA
Purity
CLIP170 Antibody is affinity chromatography purified via peptide column.
Synonyms
CLIP170, Antibody; CLIP170 Antibody; CLIP170; RSN; CLIP; CYLN1; CLIP-170; CAP-Gly domain-containing linker protein 1; Cytoplasmic linker protein 1; CAP-GLY domain containing linker protein 1; anti-CLIP1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
CLIP170 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1427
Applicable Applications for anti-CLIP1 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
CLIP170 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human CLIP170.
Buffer
CLIP170 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
CLIP170 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofuorescence of CLIP170 in human brain tissue with CLIP170 antibody at 20 μg/mL.)

product-image-AAA39361_IF13.jpg IF (Immunofluorescence) (Immunofuorescence of CLIP170 in human brain tissue with CLIP170 antibody at 20 μg/mL.)

WB (Western Blot)

(Western blot analysis of CLIP170 in rat brain tissue lysate with CLIP170 antibody at (A) 0.5 and (B) 1 μg/mL.)

product-image-AAA39361_WB15.jpg WB (Western Blot) (Western blot analysis of CLIP170 in rat brain tissue lysate with CLIP170 antibody at (A) 0.5 and (B) 1 μg/mL.)
Related Product Information for anti-CLIP1 antibody
CLIP170 Antibody: CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells for Hodgkin's disease. Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles. CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules. Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1. At least two isoforms of CLIP170 are known to exist.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
156,781 Da
NCBI Official Full Name
CAP-Gly domain-containing linker protein 1 isoform a
NCBI Official Synonym Full Names
CAP-GLY domain containing linker protein 1
NCBI Official Symbol
CLIP1
NCBI Official Synonym Symbols
RSN; CLIP; CYLN1; CLIP170; CLIP-170
NCBI Protein Information
CAP-Gly domain-containing linker protein 1; cytoplasmic linker protein 1; cytoplasmic linker protein CLIP-170; cytoplasmic linker protein 170 alpha-2; restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)
UniProt Protein Name
CAP-Gly domain-containing linker protein 1
UniProt Gene Name
CLIP1
UniProt Synonym Gene Names
CYLN1; RSN; CLIP-170
UniProt Entry Name
CLIP1_HUMAN

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Product Notes

The CLIP1 clip1 (Catalog #AAA39361) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CLIP170 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CLIP170 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the CLIP1 clip1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLIP170, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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