IHC (Immunohistochemisry)
(Detection of human COBRA1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-COBRA1 (Cat. No. AAA213993) used at a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte Plus 555 used at a dilution of 1:100.)
Rabbit anti-Human COBRA1 Polyclonal Antibody | anti-COBRA1 antibody
Rabbit anti-COBRA1 IHC Antibody, Affinity Purified
Gene Names
NELFB; COBRA1; NELF-B
Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
COBRA1, Antibody; Rabbit anti-COBRA1 IHC Antibody, Affinity Purified; cofactor of BRCA1; negative elongation factor B; negative elongation factor protein B; NELF-B; COBRA1; Negative elongation factor B; negative elongation factor complex member B; anti-COBRA1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide
Concentration
250ug/ml (varies by lot)
Applicable Applications for anti-COBRA1 antibody
IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Predicted Reactivity
Orangutan, Monkey, Gorilla, Chimpanzee, White-tufted-ear marmoset
Immunogen
Between 530 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
IHC (Immunohistochemisry)
(Detection of human COBRA1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-COBRA1 (Cat. No. AAA213993) used at a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte Plus 555 used at a dilution of 1:100.)
IHC (Immunohistochemisry)
(Detection of human COBRA1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-COBRA1 (Cat. No. AAA213993) used at a dilution of 1:250. Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte Plus 555 used at a dilution of 1:100.)
IHC (Immunohiostchemistry)
(Detection of human COBRA1 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-COBRA1 (Cat. No. AAA213993) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohiostchemistry)
(Detection of human COBRA1 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-COBRA1 (Cat. No. AAA213993) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human COBRA1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-COBRA1 (Cat. No. AAA213993) used at a dilution of 1:250. Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human COBRA1 by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-COBRA1 (Cat. No. AAA213993) used at a dilution of 1:250. Detection: DAB)
Related Product Information for anti-COBRA1 antibody
COBRA1 (Cofactor of BRCA1) is also known as NELFB (negative elongation factor E). NELFB is one of four subunits that make up the NELF transcription elongation factor. The four subunits of NELF are NELF A (WHSC2), NELFB, either NELFC or NELFD, and NELFE. NELF, along with DRB sensitivity-inducing factor (DSIF), functions to cause transcriptional pausing of RNA polymerase II. COBRA1 was originally identified in a yeast two-hybrid screen of a human ovary cDNA library using the BRCA COOH terminus repeat, BRCT1, as the bait protein. In this study, COBRA1 was found to be involved in BRCT1-mediated chromatin remodeling. COBRA1 has also been found to interact with several nuclear receptors such as ERalpha and androgen receptor to modulate their transcriptional activity.
Product Categories/Family for anti-COBRA1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
65,697 Da
NCBI Official Full Name
negative elongation factor B
NCBI Official Synonym Full Names
negative elongation factor complex member B
NCBI Official Symbol
NELFB
NCBI Official Synonym Symbols
COBRA1; NELF-B
NCBI Protein Information
negative elongation factor B
UniProt Protein Name
Negative elongation factor B
UniProt Gene Name
NELFB
UniProt Synonym Gene Names
COBRA1; KIAA1182; NELF-B
UniProt Entry Name
NELFB_HUMAN
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Product Notes
The COBRA1 nelfb (Catalog #AAA213993) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-COBRA1 IHC Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's COBRA1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the COBRA1 nelfb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COBRA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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