IHC (Immunohiostchemistry)
(Connexin 37 Antibody (GJA4) (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Connexin 37 Antibody (GJA4) (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Mouse Connexin 37 Polyclonal Antibody | anti-GJA4 antibody
Connexin 37 Antibody (C-term)
Gene Names
GJA4; CX37
Reactivity
Mouse
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Connexin 37, Antibody; Connexin 37 Antibody (C-term); Gap junction alpha-4 protein; Connexin-37; Cx37; GJA4; anti-GJA4 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Connexin 37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-333 amino acids from the C-terminal region of human Connexin 37.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Concentration
Vial Concentration: 1.15 (varies by lot)
Sequence Positions
303-333
Sequence Length
333
Applicable Applications for anti-GJA4 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Connexin 37 Antibody (GJA4) (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Connexin 37 Antibody (GJA4) (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Connexin 37 Antibody (GJA4) (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Connexin 37 Antibody (GJA4) (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(GJA4 Antibody (K317).Connexin western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the GJA4 antibody detected the GJA4 protein (arrow).)
WB (Western Blot)
(GJA4 Antibody (K317).Connexin western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the GJA4 antibody detected the GJA4 protein (arrow).)
Related Product Information for anti-GJA4 antibody
Gap junctions permit direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular communication. Gap junction channels consist of connexin protein subunits encoded by a multigene family. Erythrokeratodermia variabilis (EKV) is an autosomal dominant disorder of keratinization characterized by migratory erythematous lesions and fixed keratotic plaques. Mutations in the GJB3 gene have been reported in some but not all families, although it has been postulated that the absence of connexin 30.3 can be compensated by other connexins.
Product Categories/Family for anti-GJA4 antibody
References
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Saito, T., et al., Int. J. Cancer 86(1):67-70 (2000).
Boerma, M., et al., J. Intern. Med. 246(2):211-218 (1999).
Krutovskikh, V., et al., Carcinogenesis 17(8):1761-1763 (1996).
Reed, K.E., et al., J. Clin. Invest. 91(3):997-1004 (1993).
Saito, T., et al., Int. J. Cancer 86(1):67-70 (2000).
Boerma, M., et al., J. Intern. Med. 246(2):211-218 (1999).
Krutovskikh, V., et al., Carcinogenesis 17(8):1761-1763 (1996).
Reed, K.E., et al., J. Clin. Invest. 91(3):997-1004 (1993).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37414
NCBI Official Full Name
gap junction alpha-4 protein
NCBI Official Synonym Full Names
gap junction protein, alpha 4, 37kDa
NCBI Official Symbol
GJA4
NCBI Official Synonym Symbols
CX37
NCBI Protein Information
gap junction alpha-4 protein
UniProt Protein Name
Gap junction alpha-4 protein
UniProt Gene Name
GJA4
UniProt Synonym Gene Names
Cx37
UniProt Entry Name
CXA4_HUMAN
Similar Products
Product Notes
The GJA4 gja4 (Catalog #AAA283921) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 303-333. The Connexin 37 Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Connexin 37 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the GJA4 gja4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Connexin 37, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.