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IF (Immunofluorescence)
(Immunofluorescence of CRBN in rat testis tissue with CRBN antibody at 20 ug/mL.)
Rabbit CRBN / Cereblon Polyclonal Antibody | anti-CRBN antibody
Anti-CRBN / Cereblon Antibody (C-Terminus) IHC-plus
Gene Names
CRBN; MRT2; MRT2A
Reactivity
Mouse, Rat, Human
Applications
ELISA, Western Blot, Immunofluorescence, Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
CRBN / Cereblon, Antibody; Anti-CRBN / Cereblon Antibody (C-Terminus) IHC-plus; Rabbit Polyclonal to Human CRBN / Cereblon; Human CRBN / Cereblon; Cereblon; MRT2; MRT2A; Protein x 0001; Protein cereblon; anti-CRBN antibody
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Specificity
CRBN antibody is human, mouse and rat reactive. At least two isoforms of CRBN are known to exist; this antibody will detect both isoforms.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
442
Applicable Applications for anti-CRBN antibody
ELISA, WB (Western Blot), IF (Immunofluorescence), IHC (Immunohistochemistry)
Immunogen
CRBN / Cereblon antibody was raised against cRBN antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CRBN.
Immunogen Description
CRBN antibody was raised against a 16 amino acid peptide near the carboxy terminus of human CRBN.
Immunogen Type
Synthetic peptide
Antigen Modification
C-Terminus
Target Species
Human
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
Short term: 4 degree C
Avoid repeat freeze-thaw cycles
IF (Immunofluorescence)
(Immunofluorescence of CRBN in rat testis tissue with CRBN antibody at 20 ug/mL.)
IF (Immunofluorescence)
(Immunofluorescence of CRBN in rat testis tissue with CRBN antibody at 20 ug/mL.)
IHC (Immunohistochemisry)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemisry)
(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(Immunohistochemistry of CRBN in rat testis tissue with CRBN antibody at 5 ug/mL.)
IHC (Immunohistochemistry)
(Immunohistochemistry of CRBN in rat testis tissue with CRBN antibody at 5 ug/mL.)
Related Product Information for anti-CRBN antibody
Component of some DCX (DDB1-CUL4-X-box) E3 protein ligase complex, a complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins and is required for limb outgrowth and expression of the fibroblast growth factor FGF8. In the complex, may act as a substrate receptor. Regulates the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,475 Da
NCBI Official Full Name
protein cereblon isoform 1
NCBI Official Synonym Full Names
cereblon
NCBI Official Symbol
CRBN
NCBI Official Synonym Symbols
MRT2; MRT2A
NCBI Protein Information
protein cereblon
UniProt Protein Name
Protein cereblon
UniProt Gene Name
CRBN
UniProt Entry Name
CRBN_HUMAN
Similar Products
Product Notes
The CRBN crbn (Catalog #AAA52613) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CRBN / Cereblon Antibody (C-Terminus) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's CRBN / Cereblon can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot), IF (Immunofluorescence), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CRBN crbn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRBN / Cereblon, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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