IF (Immunofluorescence)
(Immunofluorescence of CRH in human brain tissue with CRH antibody at 20 μg/mL.)
Rabbit anti-Human CRH Polyclonal Antibody | anti-CRH antibody
CRH Antibody
Gene Names
CRH; CRF; CRH1
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
CRH antibody is affinity chromatography purified via peptide column.
Synonyms
CRH, Antibody; CRH Antibody; CRH; CRF; Corticoliberin; Corticotropin-releasing factor; corticotropin releasing hormone; anti-CRH antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
CRH antibody is human specific.
Purity/Purification
CRH antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
196
Applicable Applications for anti-CRH antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
CRH antibody was raised against a 16 amino acid peptide near the amino terminus of human CRH.
Buffer
CRH antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
CRH antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of CRH in human brain tissue with CRH antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of CRH in human brain tissue with CRH antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of CRH in human brain tissue with CRH antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of CRH in human brain tissue with CRH antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of CRH in human placenta tissue lysate with CRH antibody at (A) 1 and (B) 2 μg/ml.)
WB (Western Blot)
(Western blot analysis of CRH in human placenta tissue lysate with CRH antibody at (A) 1 and (B) 2 μg/ml.)
Related Product Information for anti-CRH antibody
Corticotropin-releasing hormone (CRH) is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress (1). In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta where it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturitio (2). Marked reduction in this protein has been observed in association with Alzheimer disease (3).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 22 kDa
Observed: 29 kDa
Observed: 29 kDa
NCBI Official Full Name
corticoliberin preproprotein
NCBI Official Synonym Full Names
corticotropin releasing hormone
NCBI Official Symbol
CRH
NCBI Official Synonym Symbols
CRF; CRH1
NCBI Protein Information
corticoliberin; corticotropin-releasing factor
UniProt Protein Name
Corticoliberin
UniProt Gene Name
CRH
UniProt Synonym Gene Names
CRF
UniProt Entry Name
CRF_HUMAN
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Product Notes
The CRH crh (Catalog #AAA40784) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CRH Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CRH can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the CRH crh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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