Rabbit anti-Human CRISP2 Polyclonal Antibody | anti-CRISP2 antibody

CRISP2 Antibody

Cat. Num. AAA39419

• Gene Names: CRISP2; CT36; TPX1; TSP1; GAPDL5; CRISP-2
• Reactivity: Human
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: CRISP2 Antibody is affinity chromatography purified via peptide column.
• Synonyms: CRISP2, Antibody; CRISP2 Antibody; CRISP2; CT36; TPX1; TSP1; GAPDL5; CRISP-2; Cysteine-rich secretory protein 2; Testis-specific protein TPX-1; cysteine-rich secretory protein 2; anti-CRISP2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: CRISP2 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 243

• Applicable Applications for anti-CRISP2 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: CRISP2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human CRISP2.
• Buffer: CRISP2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: CRISP2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of CRISP in human testis tissue with CRISP antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of CRISP2 in human testis tissue with CRISP2 antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of CRISP2 in human testis tissue lysate with CRISP2 antibody at (A) 0.5 and (B) 1 μg/mL.)

Related Product Information for anti-CRISP2 antibody

CRISP2 Antibody: The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.

NCBI and Uniprot Product Information

• NCBI GI #: 215422434
• NCBI GeneID: 7180
• NCBI Accession #: NP_001135880
• NCBI GenBank Nucleotide #: NM_001142408.2
• UniProt Accession #: P16562; Q53FF2; Q5U8Z9; Q7Z7B2; A8K8M0
• Molecular Weight: 31,581 Da
• NCBI Official Full Name: cysteine-rich secretory protein 2
• NCBI Official Synonym Full Names: cysteine-rich secretory protein 2
• NCBI Official Symbol: CRISP2
• NCBI Official Synonym Symbols: CT36; TPX1; TSP1; GAPDL5; CRISP-2
• NCBI Protein Information: cysteine-rich secretory protein 2; cancer/testis antigen 36; testis-specific protein TPX-1; testis specific protein 1 (probe H4-1 p3-1); glyceraldehyde-3-phosphate dehydrogenase-like 5
• UniProt Protein Name: Cysteine-rich secretory protein 2
• UniProt Gene Name: CRISP2
• UniProt Synonym Gene Names: GAPDL5; TPX1; CRISP-2; CT36
• UniProt Entry Name: CRIS2_HUMAN