Rabbit anti-Human CSFR Polyclonal Antibody | anti-CSFR antibody

CSFR (Phospho-Tyr561) Antibody

Cat. Num. AAA307652

• Gene Names: CSF1R; FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
• Synonyms: CSFR, Antibody; CSFR (Phospho-Tyr561) Antibody; CD115; CSF-1-R; CSFMR; FMS; M-CSFR; anti-CSFR antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of CSFR only when phosphorylated at tyrosine 561.
• Purity/Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
• Form/Format: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 972

• Applicable Applications for anti-CSFR antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen Type: Peptide-KLH
• Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 561 (N-S-Y(p)-T-F) derived from Human CSFR.
• Modification: Phospho-Tyr561
• Target Name: CSFR
• Preparation and Storage: Store at -20 degree C/1 year

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded human brain, using CSFR (Phospho-Tyr561) antibody (left)or the same antibody preincubated with blocking peptide (right).)

WB (Western Blot)

(Western blot analysis of extracts from HepG2 cells treated with PMA using CSFR (Phospho-Tyr561) Antibody.The lane on the right is treated with the antigen-specific peptide.)

Related Product Information for anti-CSFR antibody

Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Hampe A., Oncogene Res. 4:9-17(1989).Andre C., Genomics 39:216-226(1997).Liu T., J. Proteome Res. 4:2070-2080(2005).

Product Categories/Family for anti-CSFR antibody

Phospho-specific Ab

NCBI and Uniprot Product Information

• NCBI GI #: 569026720
• NCBI GeneID: 1436
• NCBI Accession #: NP_001275634.1
• NCBI GenBank Nucleotide #: NM_001288705.1
• UniProt Accession #: P07333; Q6LDW5; Q6LDY4; Q86VW7; B5A955; D3DQG2
• Molecular Weight: 33,248 Da
• NCBI Official Full Name: macrophage colony-stimulating factor 1 receptor
• NCBI Official Synonym Full Names: colony stimulating factor 1 receptor
• NCBI Official Symbol: CSF1R
• NCBI Official Synonym Symbols: FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R
• NCBI Protein Information: macrophage colony-stimulating factor 1 receptor
• UniProt Protein Name: Macrophage colony-stimulating factor 1 receptor
• UniProt Gene Name: CSF1R
• UniProt Synonym Gene Names: FMS; CSF-1-R; CSF-1R; M-CSF-R
• UniProt Entry Name: CSF1R_HUMAN