WB (Western Blot)
(Detection of human CSN3 by western blot. Samples: Whole cell lysate (50 ug) from HeLa and HEK293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-CSN3 antibody AAA210720 (lot AAA210720-1) used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
Rabbit anti-Human CSN3 Polyclonal Antibody | anti-CSN3 antibody
Rabbit anti-CSN3 Antibody, Affinity Purified
Gene Names
COPS3; CSN3; SGN3; COPS3
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Antigen Affinity Purified
Synonyms
CSN3, Antibody; Rabbit anti-CSN3 Antibody, Affinity Purified; SGN3; signalosome subunit 3; JAB1-containing signalosome subunit 3; COP9 signalosome complex subunit 3; COP9 constitutive photomorphogenic homolog subunit 3; COP9 complex subunit 3; CSN3; COP9 signalosome subunit 3; anti-CSN3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-CSN3 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Predicted Reactivity
Mouse, Rat, X. tropicalis, Chicken, Bovine, Orangutan
Immunogen
Between 373 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human CSN3 by western blot. Samples: Whole cell lysate (50 ug) from HeLa and HEK293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-CSN3 antibody AAA210720 (lot AAA210720-1) used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
WB (Western Blot)
(Detection of human CSN3 by western blot. Samples: Whole cell lysate (50 ug) from HeLa and HEK293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-CSN3 antibody AAA210720 (lot AAA210720-1) used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
WB (Western Blot)
(Detection of human CSN3 by western blot. Samples: Whole cell lysate (50 ug-E; 25 ug-T) from HEK HEK293T cells that were mock transfected (E) or transfected with a CSN3 expression construct (T).Antibody: Affinity purified rabbit anti-CSN3 antibody AAA210720 used at the indicated concentrations. Detection: Chemiluminescence with a 10 second exposure.)
WB (Western Blot)
(Detection of human CSN3 by western blot. Samples: Whole cell lysate (50 ug-E; 25 ug-T) from HEK HEK293T cells that were mock transfected (E) or transfected with a CSN3 expression construct (T).Antibody: Affinity purified rabbit anti-CSN3 antibody AAA210720 used at the indicated concentrations. Detection: Chemiluminescence with a 10 second exposure.)
IHC (Immunohistochemistry)
(Detection of human CSN3 by immunohistochemistry. Sample: FFPE section of human prostate carcinoma.Antibody: Affinity purified rabbit anti-CSN3 (Cat. No. AAA210720) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human CSN3 by immunohistochemistry. Sample: FFPE section of human prostate carcinoma.Antibody: Affinity purified rabbit anti-CSN3 (Cat. No. AAA210720) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
Related Product Information for anti-CSN3 antibody
CSN3 is one of eight subunits (CSN1 to 8) of the highly conserved COP9 signalsome (CSN) complex originally identified as a regulator of light-mediated development in Arabidopsis. Characterization of CSN from yeast to mammals reveals its function as a modulator of signal transduction pathways involved in a variety of cellular and developmental processes. One of the major functions of the CSN is the regulation of protein degradation via intersection with the ubiquitin-proteasome pathway and regulation of E3-ubiquitin ligases. The CSN also possesses kinase activity. CSN3 is the kinase associated with the CSN complex that phosphorylates signal transducers such as I-kappa-Balpha, p105, and c-Jun. Human CSN3 maps to the Smith-Magenis syndrome locus. Microdeletions in this locus results in mental retardation, skeletal abnormalities, sleep disorder, and neurobehavior anomalies.
Product Categories/Family for anti-CSN3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
COP9 signalosome complex subunit 3 [Homo sapiens]
NCBI Official Synonym Full Names
COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)
NCBI Official Symbol
COPS3
NCBI Official Synonym Symbols
CSN3; SGN3; COPS3
UniProt Protein Name
COP9 signalosome complex subunit 3
UniProt Gene Name
COPS3
UniProt Synonym Gene Names
CSN3; SGN3
UniProt Entry Name
CSN3_HUMAN
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Product Notes
The CSN3 cops3 (Catalog #AAA210720) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-CSN3 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CSN3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CSN3 cops3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CSN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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