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product-image-AAA302730_IF13.jpg IF (Immunofluorescence) (Immunofluorescence analysis of HeLa cell using CST3 antibody. Blue: DAPI for nuclear staining.)

Rabbit anti-Human CST3 Polyclonal Antibody | anti-CST3 antibody

CST3 antibody

Gene Names
CST3; ARMD11
Reactivity
Human
Applications
Immunofluorescence, Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
CST3, Antibody; CST3 antibody; ARMD11; MGC117328; CST3; anti-CST3 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total CST3 antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
146
Applicable Applications for anti-CST3 antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human CST3.
Target Name
CST3
Preparation and Storage
Store at -20 degree C

IF (Immunofluorescence)

(Immunofluorescence analysis of HeLa cell using CST3 antibody. Blue: DAPI for nuclear staining.)

product-image-AAA302730_IF13.jpg IF (Immunofluorescence) (Immunofluorescence analysis of HeLa cell using CST3 antibody. Blue: DAPI for nuclear staining.)

WB (Western Blot)

(Western blot analysis of extracts of NCI-H460 cell lines, using CST3 antibody.)

product-image-AAA302730_WB15.jpg WB (Western Blot) (Western blot analysis of extracts of NCI-H460 cell lines, using CST3 antibody.)
Related Product Information for anti-CST3 antibody
Cystatin C is a 14 kDa member of the Cystatin superfamily of cysteine protease inhibitors (1). Most cell types secrete Cystatin C (1). Cystatin C inhibits cathepsins, and thereby may function as a tumor suppressor by inhibiting cathepsin mediated tumor cell invasion (2). In addition, this tumor suppressor function can also be attributed to Cystatin C's ability to antagonize TGF-b1 signaling (2,3). Cystatin C may also modulate antigen presentation through its ability to inhibit cathepsins (4). Cystatin C is also a biomarker for kidney dysfunction (5).
Product Categories/Family for anti-CST3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15,799 Da
NCBI Official Full Name
cystatin-C
NCBI Official Synonym Full Names
cystatin C
NCBI Official Symbol
CST3
NCBI Official Synonym Symbols
ARMD11
NCBI Protein Information
cystatin-C
UniProt Protein Name
Cystatin-C
UniProt Gene Name
CST3
UniProt Entry Name
CYTC_HUMAN

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Product Notes

The CST3 cst3 (Catalog #AAA302730) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CST3 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CST3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the CST3 cst3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CST3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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