Rabbit CTGF Polyclonal Antibody | anti-CTGF antibody

RABBIT ANTI HUMAN CTGF:Biotin

Cat. Num. AAA50007

• Gene Names: CTGF; CCN2; NOV2; HCS24; IGFBP8
• Applications: Western Blot, ELISA
• Synonyms: CTGF, Antibody; RABBIT ANTI HUMAN CTGF:Biotin; anti-CTGF antibody

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Form/Format: Biotin; Purified IgG conjugated to Biotin - lyophilised
• Concentration: IgG concentration 0.1mg/ml after reconstitution (varies by lot)
• Sequence Length: 349

• Applicable Applications for anti-CTGF antibody: WB (Western Blot), ELISA
• Reconstitution: Reconstitute with 0.5ml sterile PBS containing 0.1% Bovine Serum Albumin. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. AAA Biotech recommends that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09% sodium azide is recommended.
• Immunogen: Recombinant human CTGF.; Buffer Solution
• Antiserum Preparation: Antisera to human CTGF were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
• Target Species: Human
• Preparation and Storage: Prior to reconstitution store at 4 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.; Shelf Life: 12 months from date of reconstitution.

Application Data

(Formalin fixed, paraffin embedded human breast invasive malignant carcinoma stained with Rabbit anti Human CTGF following heat mediated antigen retrieval using sodium citrate buffer (pH6.0))

Application Data

(Formalin fixed, paraffin embedded human breast invasive malignant carcinoma stained with Rabbit anti Human CTGF following heat mediated antigen retrieval using sodium citrate buffer (pH6.0))

Related Product Information for anti-CTGF antibody

Rabbit anti Human CTGF antibody specifically recognizes human CTGF (connective tissue growth factor), a 323 amino acid polypeptide and member of the CCN family of secreted cysteine rich regulatory proteins, which is produced by vascular endothelial and umbilical vein cells, and interacts with several other growth factors, including transforming growth factor beta (TGF-beta), vascular endothelial growth factor (VEGF) and bone morphogenetic proteins (BMPs). CTGF is a heparin-binding pleiotropic growth factor involved in chondrogenesis and potentially skeletogenesis. CTGF promotes the adhesion of epithelial cells and fibroblasts, stimulates integrin expression, and also promotes endothelial cell survival, migration and adhesion, implicating CTGF in angiogenesis. CTGF induces extracellular matrix formation, including the deposition of excessive collagen in fibrotic diseases, and has also been implicated in wound healing.

NCBI and Uniprot Product Information

• NCBI GI #: 4503123
• NCBI GeneID: 1490
• NCBI Accession #: NP_001892.1
• NCBI GenBank Nucleotide #: NM_001901.2
• UniProt Accession #: P29279; Q6LCY0; Q96A79; Q96QX2; Q9UDL6; E1P578
• Molecular Weight: 35,205 Da
• NCBI Official Full Name: connective tissue growth factor
• NCBI Official Synonym Full Names: connective tissue growth factor
• NCBI Official Symbol: CTGF
• NCBI Official Synonym Symbols: CCN2; NOV2; HCS24; IGFBP8
• NCBI Protein Information: connective tissue growth factor; CCN family member 2; IBP-8; IGF-binding protein 8; IGFBP-8; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8
• UniProt Protein Name: Connective tissue growth factor
• UniProt Gene Name: CTGF
• UniProt Synonym Gene Names: CCN2; HCS24; IGFBP8; IBP-8; IGF-binding protein 8; IGFBP-8
• UniProt Entry Name: CTGF_HUMAN