<
IHC (Immunohistochemistry)
(CTNND1/p120 Catenin Antibody-Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE))
Rabbit anti-Human CTNND1/p120 Catenin Polyclonal Antibody | anti-CTNND1 antibody
CTNND1/p120 Catenin Rabbit anti-Human Polyclonal Antibody
Gene Names
CTNND1; CAS; p120; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)
Reactivity
Human
Applications
Immunohistochemistry
Purity
Immunoaffinity purified
Synonyms
CTNND1/p120 Catenin, Antibody; CTNND1/p120 Catenin Rabbit anti-Human Polyclonal Antibody; PathPlus CTNND1/p120 Catenin Antibody; CTNND1; CAS; Catenin delta-1; CTNND; KIAA0384; p120; p120(CAS); p120(CTN); p120CAS; p120CTN; p120 catenin; p120-catenin; anti-CTNND1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.1% Sodium Azide
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-CTNND1 antibody
IHC (Immunohistochemistry)
Target
Human CTNND1/p120 Catenin
Immunogen
LP-11111, synthetic peptide
Conjugation
Unconjugated
Family
Catenin
Preparation and Storage
Aliquot and store undiluted at -20 degree C or below for up to 1 year. Can be stored undiluted at 4 degree C for up to 1 month. Avoid freeze-thaw cycles.
IHC (Immunohistochemistry)
(CTNND1/p120 Catenin Antibody-Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CTNND1/p120 Catenin Antibody-Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CTNND1/p120 Catenin Antibody-Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CTNND1/p120 Catenin Antibody-Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemisry)
(CTNND1/p120 Catenin Antibody-Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemisry)
(CTNND1/p120 Catenin Antibody-Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(CTNND1/p120 Catenin Antibody-Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohiostchemistry)
(CTNND1/p120 Catenin Antibody-Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CTNND1/p120 Catenin Antibody-Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE))
IHC (Immunohistochemistry)
(CTNND1/p120 Catenin Antibody-Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE))
Related Product Information for anti-CTNND1 antibody
P120 Catenin antibody is an unconjugated rabbit polyclonal antibody to p120 Catenin (CTNND1) from human. Validated for IHC.
CTNND1 (p120 Catenin, Catenin delta 1) is a member of the Armadillo protein family, which functions in adhesion between cells and signal transduction. CTNND1 stabilizes the epithelial adherens junction, an E-cadherin based complex that controls tissue integrity. Loss of CTNND1 is associated with cancer progression. Along with downregulation of e-cadherin, cytoplasmic IHC staining is observed in lobular breast carcinomas (and not invasive ductal carcinomas), with redistribution from the membrane to the cytoplasm. In normal epithelial cells as well as in invasive ductal carcinomas of the breast, CTNND1 staining is expected to be on the cell membrane.
CTNND1 (p120 Catenin, Catenin delta 1) is a member of the Armadillo protein family, which functions in adhesion between cells and signal transduction. CTNND1 stabilizes the epithelial adherens junction, an E-cadherin based complex that controls tissue integrity. Loss of CTNND1 is associated with cancer progression. Along with downregulation of e-cadherin, cytoplasmic IHC staining is observed in lobular breast carcinomas (and not invasive ductal carcinomas), with redistribution from the membrane to the cytoplasm. In normal epithelial cells as well as in invasive ductal carcinomas of the breast, CTNND1 staining is expected to be on the cell membrane.
References
J Cell Sci 2013 126:3515; J Mamm Gland Biol Neopl 2016 21(3):81; Li, 2014; Li, 2010; Histopath 2016 68:57; Am J Surg Path 2007 31:427.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
65,641 Da
NCBI Official Full Name
Homo sapiens catenin (cadherin-associated protein), delta 1 (CTNND1), transcript variant 3, mRNA
NCBI Official Synonym Full Names
catenin (cadherin-associated protein), delta 1
NCBI Official Symbol
CTNND1
NCBI Official Synonym Symbols
CAS; p120; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)
NCBI Protein Information
catenin delta-1; cadherin-associated Src substrate; p120 catenin
UniProt Protein Name
Catenin delta-1
UniProt Gene Name
CTNND1
UniProt Synonym Gene Names
KIAA0384; CAS; p120(ctn)
UniProt Entry Name
CTND1_HUMAN
Similar Products
Product Notes
The CTNND1 ctnnd1 (Catalog #AAA163031) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CTNND1/p120 Catenin Rabbit anti-Human Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CTNND1/p120 Catenin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the CTNND1 ctnnd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTNND1/p120 Catenin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.