WB (Western Blot)
(Western blot analysis of CTPS2 (arrow) using rabbit polyclonal CTPS2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CTPS2 gene.)
Rabbit CTPS2 Polyclonal Antibody | anti-CTPS2 antibody
CTPS2 Antibody (C-term)
Reactivity
Human (Predicted Reactivity: Bovine)
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CTPS2, Antibody; CTPS2 Antibody (C-term); CTP synthase 2; CTP synthetase 2; UTP--ammonia ligase 2; CTPS2; anti-CTPS2 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CTPS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 450-479 amino acids from the C-terminal region of human CTPS2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.41 (varies by lot)
Sequence Positions
450-479
Sequence Length
586
Applicable Applications for anti-CTPS2 antibody
ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Western blot analysis of CTPS2 (arrow) using rabbit polyclonal CTPS2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CTPS2 gene.)
WB (Western Blot)
(Western blot analysis of CTPS2 (arrow) using rabbit polyclonal CTPS2 Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CTPS2 gene.)
WB (Western Blot)
(CTPS2 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CTPS2 antibody detected the CTPS2 protein (arrow).)
WB (Western Blot)
(CTPS2 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CTPS2 antibody detected the CTPS2 protein (arrow).)
Related Product Information for anti-CTPS2 antibody
The protein encoded by this gene catalyzes the formation
of CTP from UTP with the concomitant deamination of glutamine to
glutamate. This protein is the rate-limiting enzyme in the
synthesis of cytosine nucleotides, which play an important role in
various metabolic processes and provide the precursors necessary
for the synthesis of RNA and DNA. Cancer cells that exhibit
increased cell proliferation also exhibit an increased activity of
this encoded protein. Thus, this protein is an attractive target
for selective chemotherapy. Three alternatively spliced transcript
variants encoding the same protein have been described for this
gene.
of CTP from UTP with the concomitant deamination of glutamine to
glutamate. This protein is the rate-limiting enzyme in the
synthesis of cytosine nucleotides, which play an important role in
various metabolic processes and provide the precursors necessary
for the synthesis of RNA and DNA. Cancer cells that exhibit
increased cell proliferation also exhibit an increased activity of
this encoded protein. Thus, this protein is an attractive target
for selective chemotherapy. Three alternatively spliced transcript
variants encoding the same protein have been described for this
gene.
Product Categories/Family for anti-CTPS2 antibody
References
Kassel, K.M., et al. J. Biol. Chem. 285(44):33727-33736(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Han, G.S., et al. J. Biol. Chem. 280(46):38328-38336(2005)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
van Kuilenburg, A.B., et al. Biochim. Biophys. Acta 1492 (2-3), 548-552 (2000) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Han, G.S., et al. J. Biol. Chem. 280(46):38328-38336(2005)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
van Kuilenburg, A.B., et al. Biochim. Biophys. Acta 1492 (2-3), 548-552 (2000) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
65678
NCBI Official Full Name
CTP synthase 2
NCBI Official Synonym Full Names
CTP synthase 2
NCBI Official Symbol
CTPS2
NCBI Protein Information
CTP synthase 2
UniProt Protein Name
CTP synthase 2
UniProt Gene Name
CTPS2
UniProt Entry Name
PYRG2_HUMAN
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Product Notes
The CTPS2 ctps2 (Catalog #AAA289692) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 450-479. The CTPS2 Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's CTPS2 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the CTPS2 ctps2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CTPS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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