IHC (Immunohiostchemistry)
(Anti-CXCR1 antibody, AAA45373, IHC(P)IHC(P): Human Lung Cancer Tissue)
Rabbit anti-Human CXCR1 Polyclonal Antibody | anti-CXCR1 antibody
Anti-CXCR1 antibody
Gene Names
CXCR1; C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
CXCR1, Antibody; Anti-CXCR1 antibody; C-X-C chemokine receptor type 1; chemokine(C-X-C motif) receptor 1; C C antibody; C C CKR 1 antibody; C-X-C chemokine receptor type 1 antibody; CCCKR1 antibody; CD 181 antibody; CD128 antibody; CD181 antibody; CD181 antigen antibody; CDw128a antibody; Chemokine(C X C motif) receptor 1 antibody; Chemokine(C X C) receptor 1 antibody; Chemokine receptor 1 antibody; CKR 1 antibody; CMKAR1 antibody; CXC-R1 antibody; CXCR 1 antibody; CXCR-1 antibody; CXCR1 antibody; CXCR1_HUMAN antibody; High affinity interleukin 8 receptor A antibody; High affinity interleukin-8 receptor A antibody; IL 8 receptor type 1 antibody; IL 8R A antibody; IL-8 receptor type 1 antibody; IL-8R A antibody; IL8 receptor antibody; IL8 receptor type 1 antibody; IL8R1 antibody; IL8RA antibody; IL8RBA antibody; Interleukin 8 receptor alpha antibody; Interleukin 8 receptor type 1 antibody; Interleukin 8 receptor type A antibody; anti-CXCR1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
350
Applicable Applications for anti-CXCR1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR1 (24-38aa DEDYSPCMLETETLN).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-CXCR1 antibody, AAA45373, IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-CXCR1 antibody, AAA45373, IHC(P)IHC(P): Human Lung Cancer Tissue)
WB (Western Blot)
(Anti-CXCR1 antibody, AAA45373, Western blottingAll lanes: Anti CXCR1 (AAA45373) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: COLO320 Whole Cell Lysate at 40ugLane 3: M231 Whole Cell Lysate at 40ugLane 4: HT1080 Whole Cell Lysate at 40ugPredicted bind size: 40KDObserved bind size: 40KD)
WB (Western Blot)
(Anti-CXCR1 antibody, AAA45373, Western blottingAll lanes: Anti CXCR1 (AAA45373) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: COLO320 Whole Cell Lysate at 40ugLane 3: M231 Whole Cell Lysate at 40ugLane 4: HT1080 Whole Cell Lysate at 40ugPredicted bind size: 40KDObserved bind size: 40KD)
Related Product Information for anti-CXCR1 antibody
Description: Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 1(CXCR1) detection. Tested with WB, IHC-P in Human.
Background: CXCR1(Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al.(1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al.(2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA(GRO) with a low affinity.
Background: CXCR1(Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al.(1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al.(2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA(GRO) with a low affinity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
39,791 Da
NCBI Official Full Name
C-X-C chemokine receptor type 1
NCBI Official Synonym Full Names
chemokine (C-X-C motif) receptor 1
NCBI Official Symbol
CXCR1
NCBI Official Synonym Symbols
C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1
NCBI Protein Information
C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; IL-8R A; IL-8 receptor type 1; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A; high affinity interleukin-8 receptor A
UniProt Protein Name
C-X-C chemokine receptor type 1
UniProt Gene Name
CXCR1
UniProt Synonym Gene Names
CMKAR1; IL8RA; CXC-R1; CXCR-1; IL-8R A
UniProt Entry Name
CXCR1_HUMAN
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Product Notes
The CXCR1 cxcr1 (Catalog #AAA45373) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CXCR1 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CXCR1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CXCR1 cxcr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CXCR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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