Rabbit CXCR3 Polyclonal Antibody | anti-CXCR3 antibody

Rabbit Polyclonal to Human CXCR3

Cat. Num. AAA52020

• Gene Names: CXCR3; GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R
• Reactivity: Gibbon, Gorilla, Human, Monkey
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: CXCR3, Antibody; Rabbit Polyclonal to Human CXCR3; Anti-CXCR3 Antibody (C-Terminus) IHC-plus; CXCR3; C-x-c chemokine receptor 3; CD183 antigen; CKR-L2; CXCR-3; CMKAR3; CD182; CD183; Cxcr3a; GPR9; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R; Chemokine (C-X-C) receptor 3; CXC-R3; Cxcr3b; G protein-coupled receptor 9; IP10 receptor; Human CXCR3; anti-CXCR3 antibody

• Host: Rabbit
• Reactivity: Gibbon, Gorilla, Human, Monkey
• Clonality: Polyclonal
• Specificity: Human CXCR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except SRRM2 (59%).
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 368

• Applicable Applications for anti-CXCR3 antibody: IHC (Immunohistochemistry)
• Target Species: Human
• Immunogen Description: Synthetic 17 amino acid peptide from C-terminus of human CXCR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Goat, Panda (82%).
• Immunogen Type: Synthetic peptide
• Immunogen: CXCR3 antibody was raised against synthetic 17 amino acid peptide from C-terminus of human CXCR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Goat, Panda (82%).
• Antigen Modification: C-Terminus
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

IHC (Immunohiostchemistry)

(Anti-CXCR3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

IHC (Immunohistochemistry)

(Anti-CXCR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Related Product Information for anti-CXCR3 antibody

CXCR3, a Chemokine Receptor, is highly similar to the interleukine 8B receptor and has been shown to mediate recruitment of T cells to sites of inflammation and retention of T-cells in the inflamed CNS. CXCR3 has been suggested to be the principal inflammatory chemokine receptor involved in intrathecal accumulation of T-cells in multiple sclerosis and diabetes. It is expressed on malignant B cells in chronic lymphoproliferative disorders (Jones et al., 2000).

Product Categories/Family for anti-CXCR3 antibody

Family: GPCR; Subfamily: Chemokine

NCBI and Uniprot Product Information

• NCBI GI #: 4504099
• NCBI GeneID: 2833
• NCBI Accession #: NP_001495.1
• NCBI GenBank Nucleotide #: NM_001504.1
• UniProt Accession #: P49682; O15185; Q7Z710; Q9P2T4; Q9P2T5; B2R982
• Molecular Weight: 28,715 Da
• NCBI Official Full Name: C-X-C chemokine receptor type 3 isoform 1
• NCBI Official Synonym Full Names: chemokine (C-X-C motif) receptor 3
• NCBI Official Symbol: CXCR3
• NCBI Official Synonym Symbols: GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R
• NCBI Protein Information: C-X-C chemokine receptor type 3; CXC-R3; CXCR-3; Mig receptor; IP10 receptor; IP-10 receptor; G protein-coupled receptor 9; chemokine (C-X-C) receptor 3; interferon-inducible protein 10 receptor
• UniProt Protein Name: C-X-C chemokine receptor type 3
• UniProt Gene Name: CXCR3
• UniProt Synonym Gene Names: GPR9; CXC-R3; CXCR-3; IP-10 receptor
• UniProt Entry Name: CXCR3_HUMAN