IHC (Immunohiostchemistry)
(CYP5A1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP5A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit CYP5A1 Polyclonal Antibody | anti-TBXAS1 antibody
CYP5A1 Antibody (Center)
Gene Names
TBXAS1; TS; TXS; CYP5; THAS; TXAS; CYP5A1; GHOSAL; BDPLT14
Reactivity
Mouse (Predicted Reactivity: Bovine, Monkey)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
CYP5A1, Antibody; CYP5A1 Antibody (Center); Thromboxane-A synthase; TXA synthase; TXS; Cytochrome P450 5A1; TBXAS1; CYP5; CYP5A1; anti-TBXAS1 antibody
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Bovine, Monkey)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This CYP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-257 amino acids from the Central region of human CYP5A1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.3 (varies by lot)
Sequence Positions
226-257
Sequence Length
534
Applicable Applications for anti-TBXAS1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(CYP5A1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP5A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(CYP5A1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CYP5A1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(CYP5A1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the CYP5A1 antibody detected the CYP5A1 protein (arrow).)
WB (Western Blot)
(CYP5A1 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the CYP5A1 antibody detected the CYP5A1 protein (arrow).)
Related Product Information for anti-TBXAS1 antibody
This gene encodes a member of the cytochrome P450
superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug
metabolism and synthesis of cholesterol, steroids and other lipids.
However, this protein is considered a member of the cytochrome P450
superfamily on the basis of sequence similarity rather than
functional similarity. This endoplasmic reticulum membrane protein
catalyzes the conversion of prostglandin H2 to thromboxane A2, a
potent vasoconstrictor and inducer of platelet aggregation. The
enzyme plays a role in several pathophysiological processes
including hemostasis, cardiovascular disease, and stroke.
Alternatively spliced transcript variants encoding different
isoforms have been found for this gene.
superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug
metabolism and synthesis of cholesterol, steroids and other lipids.
However, this protein is considered a member of the cytochrome P450
superfamily on the basis of sequence similarity rather than
functional similarity. This endoplasmic reticulum membrane protein
catalyzes the conversion of prostglandin H2 to thromboxane A2, a
potent vasoconstrictor and inducer of platelet aggregation. The
enzyme plays a role in several pathophysiological processes
including hemostasis, cardiovascular disease, and stroke.
Alternatively spliced transcript variants encoding different
isoforms have been found for this gene.
Product Categories/Family for anti-TBXAS1 antibody
References
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Wang, L.H., et al. Prostaglandins Other Lipid Mediat. 68-69, 409-422 (2002) :
Tazawa, R., et al. Arch. Biochem. Biophys. 334(2):349-356(1996)
Baek, S.J., et al. Gene 173(2):251-256(1996)
Wang, L.H., et al. Arch. Biochem. Biophys. 315(2):273-278(1994)
Wang, L.H., et al. Prostaglandins Other Lipid Mediat. 68-69, 409-422 (2002) :
Tazawa, R., et al. Arch. Biochem. Biophys. 334(2):349-356(1996)
Baek, S.J., et al. Gene 173(2):251-256(1996)
Wang, L.H., et al. Arch. Biochem. Biophys. 315(2):273-278(1994)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60518
NCBI Official Full Name
thromboxane-A synthase isoform 1
NCBI Official Synonym Full Names
thromboxane A synthase 1 (platelet)
NCBI Official Symbol
TBXAS1
NCBI Official Synonym Symbols
TS; TXS; CYP5; THAS; TXAS; CYP5A1; GHOSAL; BDPLT14
NCBI Protein Information
thromboxane-A synthase
UniProt Protein Name
Thromboxane-A synthase
UniProt Gene Name
TBXAS1
UniProt Synonym Gene Names
CYP5; CYP5A1; TXA synthase; TXS
UniProt Entry Name
THAS_HUMAN
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Product Notes
The TBXAS1 tbxas1 (Catalog #AAA283736) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 226-257. The CYP5A1 Antibody (Center) reacts with Mouse (Predicted Reactivity: Bovine, Monkey) and may cross-react with other species as described in the data sheet. AAA Biotech's CYP5A1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the TBXAS1 tbxas1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CYP5A1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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