IHC (Immunohiostchemistry)
(Immunohistochemistry of Dact2 in human brain tissue with Dact2 antibody at 2.5 ug/mL.)
Rabbit Dact2 Polyclonal Antibody | anti-Dact2 antibody
Dact2 Antibody
Gene Names
DACT2; DPR2; DAPPER2; C6orf116; bA503C24.7
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Dact2, Antibody; Dact2 Antibody; Dapper homolog 2, Dapper antagonist of beta-catenin 2; anti-Dact2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
774
Applicable Applications for anti-Dact2 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 12 amino acid peptide from near the amino terminus of human DACT2.
Target Name
Dact2
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of Dact2 in human brain tissue with Dact2 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of Dact2 in human brain tissue with Dact2 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Dact2 in SK-N-SH cell lysate with Dact2 antibody at 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of Dact2 in SK-N-SH cell lysate with Dact2 antibody at 1 ug/mL.)
Related Product Information for anti-Dact2 antibody
The Wnt signaling cascade is a conserved process in multicellular animals that plays important roles during development and can contribute to cancer and other diseases. Many members of this pathway are also expressed in the postnatal tissues such as brain. One such protein is Dact2, a member of the Dact protein family that was initially identified through binding to Disheveled (Dvl), a cytoplasmic protein essential to Wnt signaling. Dact2 is most prominent during the development of the thymus kidneys, and salivary gland. Dact2 is thought to play a role distinct from that of Dact1 with Dact2 having a greater impact on a beta-catenin-independent process termed planar cell polarity/convergent-extension signaling. Furthermore, Dact2 but not Dact1 can inhibit Nodal signaling by promoting the endocytic degradation of TGF-beta receptors. At least two isoforms of Dact2 are known to exist.
Product Categories/Family for anti-Dact2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
29,350 Da
NCBI Official Full Name
dapper homolog 2 isoform a
NCBI Official Synonym Full Names
dishevelled-binding antagonist of beta-catenin 2
NCBI Official Symbol
DACT2
NCBI Official Synonym Symbols
DPR2; DAPPER2; C6orf116; bA503C24.7
NCBI Protein Information
dapper homolog 2
UniProt Protein Name
Dapper homolog 2
UniProt Gene Name
DACT2
UniProt Synonym Gene Names
C6orf116
UniProt Entry Name
DACT2_HUMAN
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Product Notes
The Dact2 dact2 (Catalog #AAA303974) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Dact2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Dact2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Dact2 dact2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Dact2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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