WB (Western Blot)
(Western blot analysis of extracts from HeLa cells, using DBNL Antibody. The lane on the left was treated with blocking peptide.)
Rabbit DBNL Polyclonal Antibody | anti-DBNL antibody
DBNL Antibody
Gene Names
DBNL; ABP1; HIP55; SH3P7; HIP-55
Reactivity
Human, Mouse, RatPredicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
DBNL, Antibody; DBNL Antibody; ABP1; Actin-binding protein 1; Cervical mucin associated protein; Cervical mucin-associated protein; Cervical SH3P7; CMAP; Dbnl; DBNL_HUMAN; Drebrin F; drebrin like; Drebrin like protein; Drebrin-F; Drebrin-like protein; HIP 55; HIP-55; HPK1 interacting protein of 55 kDa; HPK1-interacting protein of 55 kDa; SH3 domain containing protein 7; SH3 domain-containing protein 7; SH3P7; src homology 3 domain containing protein HIP 55; anti-DBNL antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Clonality
Polyclonal
Isotype
IgG
Specificity
DBNL Antibody detects endogenous levels of DBNL.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
430
Applicable Applications for anti-DBNL antibody
WB (Western Blot)
Immunogen
A synthesized peptide derived from human DBNL.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Endosome; Cytoskeleton; Golgi Apparatus; Cytosol; Plasma Membrane
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of extracts from HeLa cells, using DBNL Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from HeLa cells, using DBNL Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Hybridoma cells, using DBNL Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Hybridoma cells, using DBNL Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-DBNL antibody
Description: Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.
Post Translational Modifications: Degraded by caspases during apoptosis.
Subunit Structure: Interacts with SHANK2, SHANK3 and SYN1. Interacts with FGD1 and DNM1. Interacts with ANKRD54. Interacts with COBL. Interacts with WASL and WIPF1 (By similarity). Interacts with MAP4K1 and PRAM1.
Similarity: The SH3 domain mediates interaction with SHANK2, SHANK3 and PRAM1. Belongs to the ABP1 family.
Post Translational Modifications: Degraded by caspases during apoptosis.
Subunit Structure: Interacts with SHANK2, SHANK3 and SYN1. Interacts with FGD1 and DNM1. Interacts with ANKRD54. Interacts with COBL. Interacts with WASL and WIPF1 (By similarity). Interacts with MAP4K1 and PRAM1.
Similarity: The SH3 domain mediates interaction with SHANK2, SHANK3 and PRAM1. Belongs to the ABP1 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Observed: 55 kDa
Predicted: 49 kDa
Predicted: 49 kDa
NCBI Official Full Name
Drebrin-like protein
NCBI Official Synonym Full Names
drebrin like
NCBI Official Symbol
DBNL
NCBI Official Synonym Symbols
ABP1; HIP55; SH3P7; HIP-55
NCBI Protein Information
drebrin-like protein
UniProt Protein Name
Drebrin-like protein
UniProt Gene Name
DBNL
UniProt Synonym Gene Names
CMAP; SH3P7; HIP-55
UniProt Entry Name
DBNL_HUMAN
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Product Notes
The DBNL dbnl (Catalog #AAA328652) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DBNL Antibody reacts with Human, Mouse, Rat Predicted: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken and may cross-react with other species as described in the data sheet. AAA Biotech's DBNL can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the DBNL dbnl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DBNL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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