Rabbit anti-Human, Mouse DCLK3 Polyclonal Antibody | anti-DCLK3 antibody

DCLK3 Antibody

Cat. Num. AAA40282

• Gene Names: DCLK3; CLR; DCK3; DCDC3C; DCAMKL3
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Western Blot, ELISA
• Purity: DCLK3 Antibody is affinity chromatography purified via peptide column.
• Synonyms: DCLK3, Antibody; DCLK3 Antibody; DCLK3; CLR; DCK3; DCDC3C; DCAMKL3; KIAA1765; Doublecortin domain-containing protein 3C; doublecortin-like kinase 3; anti-DCLK3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: DCLK3 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 648

• Applicable Applications for anti-DCLK3 antibody: IF (Immunofluorescence), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: DCLK3 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human DCLK3.
• Buffer: DCLK3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: DCLK3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of DCLK3 in mouse brain tissue with DCLK3 Antibody at 20 μg/mL.Green: DCLK3 antibody (5637)Red: Phylloidin stainingBlue: DAPI staining)

IHC (Immunohistochemisry)

(Immunohistochemistry of DCLK3 in mouse brain tissue with DCLK3 Antibody at 5 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of DLCK3 in human brain tissue with DLCK3 antibody at 20 μg/mL.)

WB (Western Blot)

(Western blot analysis of DCLK3 in K562 cell lysate with DCLK3 antibody at (A) 1 and (B) 2 μg/mL.)

Related Product Information for anti-DCLK3 antibody

DCLK3 Antibody: DCLK3 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family. DCLK3 mRNA, like that of the homologous DCLK1 and DCLK3, is highly expressed in adult brain, but only DCLK3 transcripts are present in liver and kidney, suggesting that DCLK3 may play other roles than in cortical development. The DCLK proteins are homologous to Doublecortin (DCX), a protein that is mutated in X-linked human lissencephaly. In mouse models where the DCX gene has been disrupted, DCLK1 expression increases slightly and appears to compensate for the loss of DCX, as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality, disorganized neocortical layering, and profound hippocampal cytoarchitectural disorganization.

NCBI and Uniprot Product Information

• NCBI GI #: 149589021
• NCBI GeneID: 85443
• NCBI Accession #: NP_208382
• NCBI GenBank Nucleotide #: NM_033403.1
• UniProt Accession #: Q9C098
• Molecular Weight: 73,814 Da
• NCBI Official Full Name: serine/threonine-protein kinase DCLK3
• NCBI Official Synonym Full Names: doublecortin-like kinase 3
• NCBI Official Symbol: DCLK3
• NCBI Official Synonym Symbols: CLR; DCK3; DCDC3C; DCAMKL3
• NCBI Protein Information: serine/threonine-protein kinase DCLK3; CLICK-I,II-related; doublecortin and CaM kinase-like 3; doublecortin-like and CAM kinase-like 3; doublecortin domain-containing protein 3C
• UniProt Protein Name: Serine/threonine-protein kinase DCLK3
• UniProt Gene Name: DCLK3
• UniProt Synonym Gene Names: DCAMKL3; DCDC3C; KIAA1765
• UniProt Entry Name: DCLK3_HUMAN