IHC (Immunohistochemisry)
(DCLRE1C Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCLRE1C Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human, Mouse DCLRE1C Polyclonal Antibody | anti-DCLRE1C antibody
DCLRE1C Antibody (N-term)
Gene Names
DCLRE1C; SCIDA; SNM1C; A-SCID; RS-SCID; DCLREC1C
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Synonyms
DCLRE1C, Antibody; DCLRE1C Antibody (N-term); Protein artemis; 31--; DNA cross-link repair 1C protein; Protein A-SCID; SNM1 homolog C; hSNM1C; SNM1-like protein; DCLRE1C; ARTEMIS; ASCID; SCIDA; SNM1C; anti-DCLRE1C antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
This DCLRE1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human DCLRE1C.
Purity/Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Positions
21-50
Applicable Applications for anti-DCLRE1C antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(DCLRE1C Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCLRE1C Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(DCLRE1C Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCLRE1C Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(All lanes : Anti-DCLRE1C Antibody (N-term) at 1:2000 dilutionLane 1: HepG2 whole cell lysateLane 2: HT-29 whole cell lysateLane 3: Jurkat whole cell lysateLane 4: mouse heart lysateLane 5: MCF-7 whole cell lysate Lane 5: PC-3 whole cell lysate Lane 5: ZR-75-1 whole cell lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugatedat 1/10000 dilution. Predicted band size : 78 kDa Blocking/Dilution buffer: 5% NFDM/TBST)
WB (Western Blot)
(All lanes : Anti-DCLRE1C Antibody (N-term) at 1:2000 dilutionLane 1: HepG2 whole cell lysateLane 2: HT-29 whole cell lysateLane 3: Jurkat whole cell lysateLane 4: mouse heart lysateLane 5: MCF-7 whole cell lysate Lane 5: PC-3 whole cell lysate Lane 5: ZR-75-1 whole cell lysate Lysates/proteins at 20 ?g per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugatedat 1/10000 dilution. Predicted band size : 78 kDa Blocking/Dilution buffer: 5% NFDM/TBST)
WB (Western Blot)
(Western blot analysis of DCLRE1C Antibody (N-term) in mouse heart tissue lysates (35ug/lane). DCLRE1C (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of DCLRE1C Antibody (N-term) in mouse heart tissue lysates (35ug/lane). DCLRE1C (arrow) was detected using the purified Pab.)
Related Product Information for anti-DCLRE1C antibody
DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide.
References
Beucher, A., et al. EMBO J. 28(21):3413-3427(2009)
Rivera-Munoz, P., et al. Blood 114(17):3601-3609(2009)
Wang, H., et al. J. Biol. Chem. 284(27):18236-18243(2009)
Rivera-Munoz, P., et al. Blood 114(17):3601-3609(2009)
Wang, H., et al. J. Biol. Chem. 284(27):18236-18243(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
78436
NCBI Official Full Name
protein artemis isoform a
NCBI Official Synonym Full Names
DNA cross-link repair 1C
NCBI Official Symbol
DCLRE1C
NCBI Official Synonym Symbols
SCIDA; SNM1C; A-SCID; RS-SCID; DCLREC1C
NCBI Protein Information
protein artemis
UniProt Protein Name
Protein artemis
UniProt Gene Name
DCLRE1C
UniProt Synonym Gene Names
ARTEMIS; ASCID; SCIDA; SNM1C; hSNM1C
UniProt Entry Name
DCR1C_HUMAN
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Product Notes
The DCLRE1C dclre1c (Catalog #AAA285486) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 21-50. The DCLRE1C Antibody (N-term) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DCLRE1C can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the DCLRE1C dclre1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DCLRE1C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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