IHC (Immunohiostchemistry)
(DCTN2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DCTN2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit DCTN2 Polyclonal Antibody | anti-DCTN2 antibody
DCTN2 Antibody (Center)
Gene Names
DCTN2; RBP50; DCTN50; HEL-S-77; DYNAMITIN
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
DCTN2, Antibody; DCTN2 Antibody (Center); Dynactin subunit 2; 50 kDa dynein-associated polypeptide; Dynactin complex 50 kDa subunit; DCTN-50; p50 dynamitin; DCTN2; DCTN50; anti-DCTN2 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This DCTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human DCTN2.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
192-219
Sequence Length
403
Applicable Applications for anti-DCTN2 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(DCTN2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DCTN2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(DCTN2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DCTN2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of lysate from SH-SY5Y cell line, using DCTN2 Antibody (Center). AAA288921 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
WB (Western Blot)
(Western blot analysis of lysate from SH-SY5Y cell line, using DCTN2 Antibody (Center). AAA288921 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Related Product Information for anti-DCTN2 antibody
This gene encodes a 50-kD subunit of dynactin, a
macromolecular complex consisting of 10-11 subunits ranging in size
from 22 to 150 kD. Dynactin binds to both microtubules and
cytoplasmic dynein. It is involved in a diverse array of cellular
functions, including ER-to-Golgi transport, the centripetal
movement of lysosomes and endosomes, spindle formation, chromosome
movement, nuclear positioning, and axonogenesis. This subunit is
present in 4-5 copies per dynactin molecule. It contains three
short alpha-helical coiled-coil domains that may mediate
association with self or other dynactin subunits. It may interact
directly with the largest subunit (p150) of dynactin and may affix
p150 in place.
macromolecular complex consisting of 10-11 subunits ranging in size
from 22 to 150 kD. Dynactin binds to both microtubules and
cytoplasmic dynein. It is involved in a diverse array of cellular
functions, including ER-to-Golgi transport, the centripetal
movement of lysosomes and endosomes, spindle formation, chromosome
movement, nuclear positioning, and axonogenesis. This subunit is
present in 4-5 copies per dynactin molecule. It contains three
short alpha-helical coiled-coil domains that may mediate
association with self or other dynactin subunits. It may interact
directly with the largest subunit (p150) of dynactin and may affix
p150 in place.
Product Categories/Family for anti-DCTN2 antibody
References
Jacquot, G., et al. J. Biol. Chem. 285(30):23019-23031(2010)
Inoue, M., et al. Genes Cells 13(8):905-914(2008)
Maier, K.C., et al. Traffic 9(4):481-491(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Camargo, L.M., et al. Mol. Psychiatry 12(1):74-86(2007)
Inoue, M., et al. Genes Cells 13(8):905-914(2008)
Maier, K.C., et al. Traffic 9(4):481-491(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Camargo, L.M., et al. Mol. Psychiatry 12(1):74-86(2007)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44231
NCBI Official Full Name
dynactin subunit 2 isoform 2
NCBI Official Synonym Full Names
dynactin 2 (p50)
NCBI Official Symbol
DCTN2
NCBI Official Synonym Symbols
RBP50; DCTN50; HEL-S-77; DYNAMITIN
NCBI Protein Information
dynactin subunit 2
UniProt Protein Name
Dynactin subunit 2
UniProt Gene Name
DCTN2
UniProt Synonym Gene Names
DCTN50; DCTN-50
UniProt Entry Name
DCTN2_HUMAN
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Product Notes
The DCTN2 dctn2 (Catalog #AAA288921) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 192-219. The DCTN2 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's DCTN2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the DCTN2 dctn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DCTN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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