IF (Immunofluorescence)
(Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL.)
Rabbit DDC Polyclonal Antibody | anti-DDC antibody
DDC Antibody
Gene Names
DDC; AADC
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
DDC Antibody is affinity chromatography purified via peptide column.
Synonyms
DDC, Antibody; DDC Antibody; DDC Antibody : AADC; AADC; Aromatic-L-amino-acid decarboxylase; DOPA decarboxylase; dopa decarboxylase (aromatic L-amino acid decarboxylase); anti-DDC antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
DDC antibody is human, mouse and rat reactive.
Purity/Purification
DDC Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
480
Applicable Applications for anti-DDC antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
DDC antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DDC
Buffer
DDC Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
DDC antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of DDC in human lung tissue with DDC antibody at 2.5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of DDC in human lung tissue with DDC antibody at 2.5 μg/mL.)
WB (Western Blot)
(Western blot analysis of DDC in human lung tissue lysate with DDC antibody at (A) 0.5 and (B) 1 μg/ml.)
WB (Western Blot)
(Western blot analysis of DDC in human lung tissue lysate with DDC antibody at (A) 0.5 and (B) 1 μg/ml.)
Related Product Information for anti-DDC antibody
DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1). It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2). It can form a homodimer and is expressed in the central nervous system (2). DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4). Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 53 kDa
Observed: 50 kDa
Observed: 50 kDa
NCBI Official Full Name
aromatic-L-amino-acid decarboxylase isoform 1
NCBI Official Synonym Full Names
dopa decarboxylase (aromatic L-amino acid decarboxylase)
NCBI Official Symbol
DDC
NCBI Official Synonym Symbols
AADC
NCBI Protein Information
aromatic-L-amino-acid decarboxylase
UniProt Protein Name
Aromatic-L-amino-acid decarboxylase
UniProt Gene Name
DDC
UniProt Synonym Gene Names
AADC; AADC; DDC
UniProt Entry Name
DDC_HUMAN
Similar Products
Product Notes
The DDC ddc (Catalog #AAA40649) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DDC Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DDC can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the DDC ddc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DDC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.