Rabbit anti-Human, Mouse DDR2 Polyclonal Antibody | anti-DDR2 antibody

DDR2 Antibody

Cat. Num. AAA232870

• Gene Names: DDR2; TKT; MIG20a; NTRKR3; TYRO10
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: >95%, Protein G purified
• Synonyms: DDR2, Antibody; DDR2 Antibody; Discoidin domain-containing receptor 2; Discoidin domain receptor 2; CD167 antigen-like family member B; Discoidin domain-containing receptor tyrosine kinase 2; Neurotrophic tyrosine kinase; receptor-related 3; Receptor protein-tyrosine kinase TKT; Tyrosine-protein kinase TYRO10; CD167b; DDR2; NTRKR3; TKT; TYRO10; anti-DDR2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >95%, Protein G purified
• Form/Format: Liquid
• Sequence Length: 855

• Applicable Applications for anti-DDR2 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Immunogen: Recombinant Human Discoidin domain-containing receptor 2 protein (447-540AA)
• Storage Buffer: Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
• Conjugate: Non-conjugated
• Species: Human
• Research Area: Neuroscience
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7555 / sc-8989
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

IHC (Immunohistochemisry)

(Immunofluorescent analysis of HepG2 cells using AAA232870 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human heart tissue using AAA232870 at dilution of 1:100)

WB (Western Blot)

(Western BlotPositive WB detected in: Hela whole cell lysate,Jurkat whole cell lysate,HEK293 whole cell lysate,NIH/3T3 whole cell lysate,A549 whole cell lysateAll lanes: DDR2 antibody at 3.5ug/mlSecondaryGoat polyclonal to rabbit IgG at 1/50000 dilutionPredicted band size: 97 KDaObserved band size: 97 KDa)

Related Product Information for anti-DDR2 antibody

Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing.

NCBI and Uniprot Product Information

• NCBI GI #: 62420886
• NCBI GeneID: 4921
• NCBI Accession #: NP_001014796.1
• NCBI GenBank Nucleotide #: NM_001014796.1
• UniProt Accession #: Q16832; Q7Z730
• NCBI Official Full Name: discoidin domain-containing receptor 2
• NCBI Official Synonym Full Names: discoidin domain receptor tyrosine kinase 2
• NCBI Official Symbol: DDR2
• NCBI Official Synonym Symbols: TKT; MIG20a; NTRKR3; TYRO10
• NCBI Protein Information: discoidin domain-containing receptor 2
• UniProt Protein Name: Discoidin domain-containing receptor 2
• UniProt Gene Name: DDR2
• UniProt Synonym Gene Names: NTRKR3; TKT; TYRO10; Discoidin domain receptor 2
• UniProt Entry Name: DDR2_HUMAN