WB (Western Blot)
(Anti-Decorin antibody, AAA45120, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Rat Lung Tissue LysateLane 3: Rat Spleen Tissue LysateLane 4: SMMC Cell LysateLane 5: SMMC Cell Lysate)
Rabbit Decorin Polyclonal Antibody | anti-DCN antibody
Anti-Decorin antibody
Gene Names
DCN; CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
Decorin, Antibody; Anti-Decorin antibody; Decorin; decorin; Bone proteoglycan II antibody; CSCD antibody; DCN antibody; DCN protein antibody; Decorin antibody; Decorin proteoglycan antibody; Dermatan sulphate proteoglycans II antibody; DKFZp686J19238 antibody; DSPG 2 antibody; DSPG2 antibody; PG 40 antibody; PG II antibody; PG S2 antibody; PG-S2 antibody; PG40 antibody; PGII antibody; PGS 2 antibody; PGS2 antibody; PGS2_HUMAN antibody; Proteoglycan core protein antibody; SLRR1B antibody; Small leucine rich protein 1B antibody; anti-DCN antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
359
Applicable Applications for anti-DCN antibody
WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Decorin (343-359aa TFRCVYVRSAIQLGNYK), identical to the related mouse sequence, and different from the related rat sequence by three amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
WB (Western Blot)
(Anti-Decorin antibody, AAA45120, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Rat Lung Tissue LysateLane 3: Rat Spleen Tissue LysateLane 4: SMMC Cell LysateLane 5: SMMC Cell Lysate)
WB (Western Blot)
(Anti-Decorin antibody, AAA45120, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Rat Lung Tissue LysateLane 3: Rat Spleen Tissue LysateLane 4: SMMC Cell LysateLane 5: SMMC Cell Lysate)
WB (Western Blot)
(Anti-Decorin antibody, AAA45120, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Rat Kidney Tissue LysateLane 3: SMMC Cell Lysate)
WB (Western Blot)
(Anti-Decorin antibody, AAA45120, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Rat Kidney Tissue LysateLane 3: SMMC Cell Lysate)
Related Product Information for anti-DCN antibody
Description: Rabbit IgG polyclonal antibody for Decorin(DCN) detection. Tested with WB in Human, Mouse, Rat.
Background: Decorin is a proteoglycan on average 90-140 kilodaltons(kD) in size. The human decorin gene spans more than 38 kb and contains 8 exons and very large introns, 2 of which are 5.4 and more than 13.2 kb. And the human decorin gene is mapped to 12q21.3. It belongs to the small leucine-rich proteoglycan(SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan(GAG) chain consisting of either chondroitin sulfate(CS) or dermatan sulfate(DS). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are though to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. And it also may play a role in epithelial/mesenchymal interactions during organ development and shaping. Decorin has been shown to have anti-tumorigenic properties in an experimental murine tumor model and is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for the decorin gene. Mutations in the decorin gene are associated with congenital stromal corneal dystrophy.
Background: Decorin is a proteoglycan on average 90-140 kilodaltons(kD) in size. The human decorin gene spans more than 38 kb and contains 8 exons and very large introns, 2 of which are 5.4 and more than 13.2 kb. And the human decorin gene is mapped to 12q21.3. It belongs to the small leucine-rich proteoglycan(SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan(GAG) chain consisting of either chondroitin sulfate(CS) or dermatan sulfate(DS). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are though to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. And it also may play a role in epithelial/mesenchymal interactions during organ development and shaping. Decorin has been shown to have anti-tumorigenic properties in an experimental murine tumor model and is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for the decorin gene. Mutations in the decorin gene are associated with congenital stromal corneal dystrophy.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
8,266 Da
NCBI Official Full Name
Decorin
NCBI Official Synonym Full Names
decorin
NCBI Official Symbol
DCN
NCBI Official Synonym Symbols
CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B
NCBI Protein Information
decorin; PG-S2; bone proteoglycan II; decorin proteoglycan; proteoglycan core protein; small leucine-rich protein 1B; dermatan sulphate proteoglycans II
UniProt Protein Name
Decorin
UniProt Gene Name
DCN
UniProt Synonym Gene Names
SLRR1B
UniProt Entry Name
PGS2_HUMAN
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Product Notes
The DCN dcn (Catalog #AAA45120) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Decorin antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Decorin can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the DCN dcn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Decorin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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