Rabbit DEDAF Polyclonal Antibody | anti-RYBP antibody

DEDAF Antibody

Cat. Num. AAA39870

• Gene Names: RYBP; AAP1; DEDAF; YEAF1
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: DEDAF Antibody is affinity chromatography purified via peptide column.
• Synonyms: DEDAF, Antibody; DEDAF Antibody; DEDAF; AAP1; YEAF1; RING1 and YY1-binding protein; Apoptin-associating protein 1; APAP-1; RING1 and YY1 binding protein; anti-RYBP antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: DEDAF Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1036

• Applicable Applications for anti-RYBP antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: DEDAF antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DEDAF.
• Buffer: DEDAF Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of DEDAF in mouse liver tissue with DEDAF antibody at 20 μg/ml.)

IHC (Immunohistochemistry)

(Immunohistochemistry of DEDAF in mouse liver tissue with DEDAF antibody at 10 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of DEDAF in A549 cells with DEDAF antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of DEDAF in mouse liver tissue with DEDAF antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of DEDAF expression in human A549 (lane A), HepG2 (lane B), and mouse 3T3 (lane C) cell lysates with DEDAF antibody at 1 μg /ml.)

Related Product Information for anti-RYBP antibody

DEDAF Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. Several molecules including caspases and adaptor FADD contain DEDs. A novel protein that interacts with DED of caspase-8 and 10, and FADD was identified recently and designated DEDAF for DED associated factor. DEDAF is identical to the transcriptional repressor RYBP. DEDAF/RYBP is expressed in multiple tissues and cell lines. DEDAF interacts with FADD and augments the formation of CD95/FADD/capase-8 complexes at the cell membrane, and interacts with DED-containing DNA biding protein (DEDD) in the nucleus indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.

NCBI and Uniprot Product Information

• NCBI GI #: 5802963
• NCBI GeneID: 23429
• UniProt Accession #: Q8N488; Q9P2W5; Q9UMW4
• Molecular Weight: 32 kDa
• NCBI Official Full Name: Homo sapiens death effector domain-associated factor mRNA, complete cds
• NCBI Official Synonym Full Names: RING1 and YY1 binding protein
• NCBI Official Symbol: RYBP
• NCBI Official Synonym Symbols: AAP1; DEDAF; YEAF1
• NCBI Protein Information: RING1 and YY1-binding protein; APAP-1; DED-associated factor; ring1 interactor RYBP; apoptin-associating protein 1; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1; death effector domain-associated factor
• UniProt Protein Name: RING1 and YY1-binding protein
• UniProt Gene Name: RYBP
• UniProt Synonym Gene Names: DEDAF; YEAF1; APAP-1; DED-associated factor
• UniProt Entry Name: RYBP_HUMAN