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product-image-AAA118478_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AAA118478 at dilution of 1:100)

Rabbit anti-Human DIS3L Polyclonal Antibody | anti-DIS3L antibody

DIS3L Antibody

Gene Names
DIS3L; DIS3L1
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
>95%, Protein G Purified
Synonyms
DIS3L, Antibody; DIS3L Antibody; DIS3-like exonuclease 1 (EC:3.1.13.-); DIS3L; DIS3L1; KIAA1955; anti-DIS3L antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
1054
Applicable Applications for anti-DIS3L antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human DIS3-like exonuclease 1 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-242579
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AAA118478 at dilution of 1:100)

product-image-AAA118478_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using AAA118478 at dilution of 1:100)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human colon cancer using AAA118478 at dilution of 1:100)

product-image-AAA118478_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human colon cancer using AAA118478 at dilution of 1:100)

WB (Western Blot)

(Western blotAll lanes: DIS3L antibody at 6ug/mlLane 1: Hela whole cell lysateLane 2: HepG-2 whole cell lysateLane 3: MCF7 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 121,106,87,112 kDaObserved band size: 121 kDa)

product-image-AAA118478_WB15.jpg WB (Western Blot) (Western blotAll lanes: DIS3L antibody at 6ug/mlLane 1: Hela whole cell lysateLane 2: HepG-2 whole cell lysateLane 3: MCF7 whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 121,106,87,112 kDaObserved band size: 121 kDa)
Related Product Information for anti-DIS3L antibody
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
111,119 Da
NCBI Official Full Name
DIS3-like exonuclease 1 isoform 1
NCBI Official Synonym Full Names
DIS3 like exosome 3'-5' exoribonuclease
NCBI Official Symbol
DIS3L
NCBI Official Synonym Symbols
DIS3L1
NCBI Protein Information
DIS3-like exonuclease 1
UniProt Protein Name
DIS3-like exonuclease 1
UniProt Gene Name
DIS3L
UniProt Synonym Gene Names
DIS3L1; KIAA1955
UniProt Entry Name
DI3L1_HUMAN

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Product Notes

The DIS3L dis3l (Catalog #AAA118478) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DIS3L Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DIS3L can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the DIS3L dis3l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DIS3L, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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