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product-image-AAA231016_IF13.jpg IF (Immunofluorescence) (Immunofluorescent analysis of HepG2 cells using AAA231016 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Rabbit anti-Human DOCK3 Polyclonal Antibody | anti-DOCK3 antibody

DOCK3 Antibody

Gene Names
DOCK3; PBP; MOCA
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, ELISA
Purity
>95%, Protein G purified
Synonyms
DOCK3, Antibody; DOCK3 Antibody; Dedicator of cytokinesis protein 3; Modifier of cell adhesion; Presenilin-binding protein; PBP; DOCK3; KIAA0299; MOCA; anti-DOCK3 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
2030
Applicable Applications for anti-DOCK3 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA
Species
Human
Immunogen
Recombinant human Dedicator of cytokinesis protein 3 protein
Conjugate
Non-conjugated
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-70182 / sc-70184 / sc-70185 / sc-135232
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IF (Immunofluorescence)

(Immunofluorescent analysis of HepG2 cells using AAA231016 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

product-image-AAA231016_IF13.jpg IF (Immunofluorescence) (Immunofluorescent analysis of HepG2 cells using AAA231016 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human brain tissue using AAA231016 at dilution of 1:100)

product-image-AAA231016_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded human brain tissue using AAA231016 at dilution of 1:100)
Related Product Information for anti-DOCK3 antibody
Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
233,103 Da
NCBI Official Full Name
dedicator of cytokinesis protein 3
NCBI Official Synonym Full Names
dedicator of cytokinesis 3
NCBI Official Symbol
DOCK3
NCBI Official Synonym Symbols
PBP; MOCA
NCBI Protein Information
dedicator of cytokinesis protein 3
UniProt Protein Name
Dedicator of cytokinesis protein 3
UniProt Gene Name
DOCK3
UniProt Synonym Gene Names
KIAA0299; MOCA; PBP
UniProt Entry Name
DOCK3_HUMAN

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Product Notes

The DOCK3 dock3 (Catalog #AAA231016) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DOCK3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DOCK3 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the DOCK3 dock3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DOCK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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